@article {5288,
	title = {A prospective randomised controlled trial comparing three alternative bearing surfaces in primary total hip replacement.},
	journal = {J Bone Joint Surg Br},
	volume = {94},
	year = {2012},
	month = {2012 Apr},
	pages = {459-65},
	abstract = {The ideal bearing surface for young patients undergoing total hip replacement (THR) remains controversial. We report the five-year results of a randomised controlled trial comparing the clinical and radiological outcomes of 102 THRs in 91 patients who were <~65~years of age. These patients were randomised to receive a cobalt-chrome on ultra-high-molecular-weight polyethylene, cobalt-chrome on highly cross-linked polyethylene, or a ceramic-on-ceramic bearing. In all, 97 hip replacements in 87 patients were available for review at five years. Two hips had been revised, one for infection and one for peri-prosthetic fracture. At the final follow-up there were no significant differences between the groups for the mean Western Ontario and McMaster Universities osteoarthritis index (pain, p = 0.543; function, p = 0.10; stiffness, p = 0.99), Short Form-12 (physical component, p = 0.878; mental component, p = 0.818) or Harris hip scores (p = 0.22). Radiological outcomes revealed no significant wear in the ceramic group. Comparison of standard and highly cross-linked polyethylene, however, revealed an almost threefold difference in the mean annual linear wear rates (0.151 mm/year versus 0.059 mm/year, respectively) (p < 0.001).},
	keywords = {Adult, Arthroplasty, Replacement, Hip, Ceramics, Chromium, Cobalt, Female, Follow-Up Studies, Hip Prosthesis, Humans, Male, Middle Aged, Osteoarthritis, Hip, Polyethylene, Prospective Studies, Prosthesis Design, Prosthesis Failure, Severity of Illness Index, Treatment Outcome, Young Adult},
	issn = {2044-5377},
	doi = {10.1302/0301-620X.94B4.27735},
	author = {Nikolaou, V S and Edwards, M R and Bogoch, E and Schemitsch, E H and Waddell, J P}
}
