@article {20352,
	title = {A Nationwide Study about the Dispersal Patterns of the Predominant HIV-1 Subtypes A1 and B in Greece: Inference of the Molecular Transmission Clusters},
	journal = {VirusesVirusesViruses},
	volume = {12},
	number = {10},
	year = {2020},
	note = {1999-4915Kostaki, Evangelia GeorgiaOrcid: 0000-0002-3346-0930Gova, MariaAdamis, GeorgiosXylomenos, GeorgiosChini, MariaMangafas, NikosLazanas, MariosMetallidis, SimeonOrcid: 0000-0002-3869-5341Tsachouridou, OlgaPapastamopoulos, VasileiosChatzidimitriou, DimitriosOrcid: 0000-0001-9656-5898Kakalou, EleniAntoniadou, AnastasiaPapadopoulos, AntoniosPsichogiou, MinaBasoulis, DimitriosPilalas, DimitriosOrcid: 0000-0003-1362-8027Papageorgiou, IfigeneiaParaskeva, DimitraChrysos, GeorgiosOrcid: 0000-0002-8272-8446Paparizos, VasileiosKourkounti, SofiaSambatakou, HelenBolanos, VasileiosSipsas, Nikolaos VOrcid: 0000-0001-6955-3453Lada, MalvinaOrcid: 0000-0001-9979-1495Barbounakis, EmmanouilKantzilaki, EvrikleiaPanagopoulos, PeriklisOrcid: 0000-0003-0643-1090Petrakis, VasilisDrimis, SteliosGogos, CharalambosHatzakis, AngelosBeloukas, ApostolosOrcid: 0000-0001-5639-0528Skoura, LemoniaParaskevis, DimitriosOrcid: 0000-0001-6167-7152Journal ArticleResearch Support, Non-U.S. Gov{\textquoteright}tViruses. 2020 Oct 19;12(10):1183. doi: 10.3390/v12101183.},
	month = {Oct 19},
	edition = {2020/10/23},
	abstract = {Our aim was to investigate the dispersal patterns and parameters associated with local molecular transmission clusters (MTCs) of subtypes A1 and B in Greece (predominant HIV-1 subtypes). The analysis focused on 1751 (28.4\%) and 2575 (41.8\%) sequences of subtype A1 and B, respectively. Identification of MTCs was based on phylogenetic analysis. The analyses identified 38 MTCs including 2-1518 subtype A1 sequences and 168 MTCs in the range of 2-218 subtype B sequences. The proportion of sequences within MTCs was 93.8\% (1642/1751) and 77.0\% (1982/2575) for subtype A1 and B, respectively. Transmissions within MTCs for subtype A1 were associated with risk group (Men having Sex with Men vs. heterosexuals, OR = 5.34, p < 0.001) and Greek origin (Greek vs. non-Greek origin, OR = 6.05, p < 0.001) and for subtype B, they were associated with Greek origin (Greek vs. non-Greek origin, OR = 1.57, p = 0.019), younger age (OR = 0.96, p < 0.001), and more recent sampling (time period: 2011-2015 vs. 1999-2005, OR = 3.83, p < 0.001). Our findings about the patterns of across and within country dispersal as well as the parameters associated with transmission within MTCs provide a framework for the application of the study of molecular clusters for HIV prevention.},
	keywords = {*dispersal patterns, *Greece, *human immunodeficiency virus (HIV), *local transmission, *Molecular Epidemiology, *phylogenetic analysis, *phylogeographic analysis, *transmission clusters},
	isbn = {1999-4915},
	author = {Kostaki, E. G. and Gova, M. and Adamis, G. and Xylomenos, G and Chini, M and Mangafas, N. and Lazanas, M and Metallidis, S. and Tsachouridou, O. and Papastamopoulos, V and Chatzidimitriou, D. and Kakalou, E. and Antoniadou, A and Papadopoulos, A. and Psichogiou, M and Basoulis, D. and Pilalas, D. and Papageorgiou, I. and Paraskeva, D. and Chrysos, G and Paparizos, V and Kourkounti, S and Sambatakou, H and Bolanos, V. and Sipsas, N V and Lada, M and Barbounakis, E. and Kantzilaki, E. and Panagopoulos, P and Petrakis, V. and Drimis, S and Gogos, C. and Hatzakis, A and Beloukas, A. and Skoura, L. and Paraskevis, D}
}
