@article {5963,
	title = {Determinants of secondary hyperparathyroidism in bariatric patients after roux-en-y gastric bypass or sleeve gastrectomy: A pilot study},
	journal = {International Journal of Endocrinology},
	volume = {2015},
	year = {2015},
	month = {2015///},
	abstract = {{\textcopyright} 2015 Andreas Alexandrou et al. Objective. Nutritional deficiencies are common after bariatric surgery. We aimed to assess the prevalence and possible predictors of secondary hyperparathyroidism (SHPT) in bariatric patients. Methods. A total of 95 patients who had undergone Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) were assessed after a median of 3 years after surgery. Anthropometric/demographic and weight-loss parameters were compared according to the presence of SHPT, independently for men/premenopausal women and postmenopausal women. Results. SHPT was highly prevalent (men/premenopausal women, 52.1\%; postmenopausal women, 31.9\%). Among men/premenopausal women, multivariate analysis indicated that SHPT was predicted by (a) 25-hydroxyvitamin D levels (Exp(B) = 0.869, P-value = 0.037), independently of age, sex, smoking; (b) calcium (Exp(B) = 0.159, P-value = 0.033) and smoking, independently of age and sex; (c) magnesium (Exp(B) = 0.026, P-value = 0.046) and smoking, independently of age and sex. Among postmenopausal women, SHPT was predicted by menopausal age independently of age, smoking, and levels of 25-hydroxyvitamin D or calcium. The development of SHPT was not associated with the type of surgery. Conclusions. RYGB and SG exhibited similar effects regarding the regulation of the hypothalamus-pituitary-parathyroid axis after surgery. Vitamin D status and menopausal age appear to determine SHPT on the long term. SHPT should be sought and vigorously treated with calcium and vitamin D supplementation.},
	author = {Alexandrou, A and Tsoka, E. and Armeni, E. and Rizos, D. and Diamantis, T and Augoulea, A. and Panoulis, C. and Liakakos, T. and Lambrinoudaki, I.}
}
