@article {6005,
	title = {Expression of CEA, CA-125 and SCC antigen by biological fluids associated with pregnancy},
	journal = {European Journal of Obstetrics and Gynecology and Reproductive Biology},
	volume = {44},
	year = {1992},
	month = {1992///},
	pages = {215 - 220},
	abstract = {Carcinoembryonic antigen (CEA), cancer antigen 125 (CA-125) and squamous cell carcinoma (SCC) antigen were measured in 56 full-termed pregnancies by enzyme-immunoassays (EIA-MEIA). The measurements were done in maternal serum (MS), umbilical cord blood (UCB) and amniotic fluid (AF) samples, during delivery. Very high antigen levels were found in AF samples (median: CEA = 124 ng/ml; CA-125 = 710 U/ml; SCC = 710 ng/ml) compared to UCB and MS. CEA and SCC showed significantly lower value{\textquoteright}s in MS (0.6 and 1.7 ng/ml, respectively) than in UCB (1.6 ng/ml, P = 7.7 {\texttimes} 10-9; 3.55 ng/ml, P = 6.5 {\texttimes} 10-6, respectively), while CA-125 had significantly higher values in MS (6 U/ml) than in UCB (0.0 U/ml, P = 17 {\texttimes} 10-6; Wilcoxon paired test). All CEA values in MS were below cut-off (<= 5 ng/ml), while 10\% of CA-125 and 30\% of SCC values were above cut-off (<= 35 U /ml and <= 2.5 ng/ml, respectively). Amniotic fluid CEA with meconium had higher values (P = 0.0002), while the highest CA-125 values in AF samples were found in primiparae (P = 0.02). Moreover SCC in AF samples from vaginal delivered pregnancies showed significantly higher values, compared to those from cesarean section (P = 4.2 {\texttimes} 10-7; Mann-Whitney U-test). Thus, our findings suggest that pregnancy has an influence on maternal serum SCC and CA-125 values, while CEA is independent of gestation and seems to conserve its diagnostic value during pregnancy as well. {\textcopyright} 1992.},
	keywords = {Cancer antigen 125, Carcinoembryonic antigen, Oncofetal antigen, Squamous cell carcinoma antigen},
	author = {Sarandakou, A. and Kontoravdis, A. and Kontogeorgi, Z. and Rizos, D. and Phocas, I.}
}
