@article {6054,
	title = {First-trimester pregnancy termination with 800 microg of vaginal misoprostol every 12 h.},
	journal = {The European journal of contraception \& reproductive health care : the official journal of the European Society of Contraception},
	volume = {10},
	year = {2005},
	month = {2005///},
	pages = {249 - 54},
	abstract = {The objective of the study was to evaluate the efficacy and safety of 800 microg of misoprostol every 12 h, for a period of 36 h for pharmacological abortion. A group of 162 volunteer women with gestations between 50 and 63 days received misoprostol every 12 h up to a maximum of three doses for abortion. Outcome measures assessed included: successful abortion (complete abortion without requiring surgery), side effects, and a decrease in hemoglobin, mean time of vaginal bleeding, mean expulsion time and mean time of returning of menses. Complete abortion occurred in 148 of 162 (91\%, 95\% confidence interval 87.95) patients. The mean decrease in hemoglobin was statistically significant (p = 0.001). Vaginal bleeding lasted 8.0 +/- 3.2 days, spotting 8.0 +/- 3.5 days, and total bleeding 16 +/- 4.0 days. The mean expulsion time was 8.5 +/- 4.0 h. According to the observed outcomes, 800 microg of misoprostol vaginally could be a valid method to terminate pregnancies up to 9 weeks of gestation.},
	keywords = {Abortifacient Agents, Abortion, Administration, Adolescent, Adult, Drug Administration Schedule, Female, First, Humans, Induced, Induced: methods, Intravaginal, Misoprostol, Misoprostol: administration \& dosage, Misoprostol: adverse effects, Nonsteroidal, Nonsteroidal: administration, Nonsteroidal: adverse effect, Pregnancy, Pregnancy Trimester, Treatment Outcome},
	isbn = {1362518050},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/16448952},
	author = {Salakos, N. and Kountouris, A. and Botsis, D. and Rizos, D. and Gregoriou, O. and Detsis, G. and Creatsas, G.}
}
