TY - JOUR T1 - Outpatient management of chronic heart failure JF - Expert Opin PharmacotherExpert Opin PharmacotherExpert Opin Pharmacother Y1 - 2015 A1 - Kaldara, E. A1 - Sanoudou, D. A1 - Adamopoulos, S A1 - Nanas, J.N. KW - Adrenergic beta-Antagonists/therapeutic use KW - Angiotensin-Converting Enzyme Inhibitors/therapeutic use KW - Chronic Disease KW - Clinical Trials as Topic KW - Disease Management KW - Heart Failure/*drug therapy/etiology KW - Humans KW - Outpatients KW - Ventricular Dysfunction, Left/complications/drug therapy AB - INTRODUCTION: Heart failure (HF) treatment attracts a share of intensive research because of its poor HF prognosis. In the past decades, the prognosis of HF has improved considerably, mainly as a consequence of the progress that has been made in the pharmacological management of HF. AREAS COVERED: This article reviews the outpatient pharmacological management of chronic HF due to left ventricular systolic dysfunction and offers recommendations on the use of various drugs. In addition, the present article attempts to provide practical therapeutic algorithms based on current clinical strategies. EXPERT OPINION: Continued research directed toward identifying factors associated with high pharmacotherapy guideline adherence and understanding of variants that influence response to drugs will hopefully halt or reverse the major pathophysiological mechanisms involved in this syndrome. VL - 16 SN - 1744-7666 (Electronic)1465-6566 (Linking) N1 - Kaldara, ElisabethSanoudou, DespinaAdamopoulos, StamatisNanas, John NengReviewEngland2014/12/07 06:00Expert Opin Pharmacother. 2015 Jan;16(1):17-41. doi: 10.1517/14656566.2015.978286. Epub 2014 Dec 5. JO - Expert opinion on pharmacotherapyExpert opinion on pharmacotherapy ER -