<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gkouskou, K.</style></author><author><style face="normal" font="default" size="100%">Vlastos, I.</style></author><author><style face="normal" font="default" size="100%">Karkalousos, P.</style></author><author><style face="normal" font="default" size="100%">Chaniotis, D.</style></author><author><style face="normal" font="default" size="100%">Sanoudou, D.</style></author><author><style face="normal" font="default" size="100%">Eliopoulos, A. G.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The &quot;Virtual Digital Twins&quot; Concept in Precision Nutrition</style></title><secondary-title><style face="normal" font="default" size="100%">Adv NutrAdv NutrAdv Nutr</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Advances in nutrition</style></alt-title><short-title><style face="normal" font="default" size="100%">Advances in nutritionAdvances in nutrition</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">*Nutritional Status</style></keyword><keyword><style  face="normal" font="default" size="100%">Gastrointestinal Microbiome</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Life Style</style></keyword><keyword><style  face="normal" font="default" size="100%">Obesity</style></keyword><keyword><style  face="normal" font="default" size="100%">Precision Medicine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov 16</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">6</style></number><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1405-1413</style></pages><isbn><style face="normal" font="default" size="100%">2156-5376 (Electronic)2161-8313 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Nutritional and lifestyle changes remain at the core of healthy aging and disease prevention. Accumulating evidence underscores the impact of genetic, metabolic, and host gut microbial factors on individual responses to nutrients, paving the way for the stratification of nutritional guidelines. However, technological advances that incorporate biological, nutritional, lifestyle, and health data at an unprecedented scale and depth conceptualize a future where preventative dietary interventions will exceed stratification and will be highly individualized. We herein discuss how genetic information combined with longitudinal metabolomic, immune, behavioral, and gut microbial parameters, and bioclinical variables could define a digital replica of oneself, a &quot;virtual digital twin,&quot; which could serve to guide nutrition in a personalized manner. Such a model may revolutionize the management of obesity and its comorbidities, and provide a pillar for healthy aging.</style></abstract><accession-num><style face="normal" font="default" size="100%">32770212</style></accession-num><notes><style face="normal" font="default" size="100%">Gkouskou, KalliopiVlastos, IoannisKarkalousos, PetrosChaniotis, DimitriosSanoudou, DespinaEliopoulos, Aristides GengBethesda, Md.2020/08/10 06:00Adv Nutr. 2020 Nov 16;11(6):1405-1413. doi: 10.1093/advances/nmaa089.</style></notes><custom2><style face="normal" font="default" size="100%">7666894</style></custom2><auth-address><style face="normal" font="default" size="100%">Department of Biology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.Embiodiagnostics, Biology Research Company, Heraklion, Crete, Greece.Department of Biomedical Sciences, University of West Attica, Athens, Greece.Clinical Genomics and Pharmacogenomics Unit, 4th Department of Internal Medicine, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.Center for New Biotechnologies and Precision Medicine, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.Center of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.</style></auth-address></record></records></xml>