<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vafiadaki, E.</style></author><author><style face="normal" font="default" size="100%">Arvanitis, DA</style></author><author><style face="normal" font="default" size="100%">Sanoudou, D.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Muscle LIM Protein: Master regulator of cardiac and skeletal muscle functions</style></title><secondary-title><style face="normal" font="default" size="100%">GeneGeneGene</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Gene</style></alt-title><short-title><style face="normal" font="default" size="100%">GeneGene</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Heart Diseases/physiopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">LIM-Homeodomain Proteins/chemistry/genetics/*physiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Muscle Proteins/chemistry/genetics/*physiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Muscles/*physiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Muscular Diseases/physiopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Protein Structure, Tertiary</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jul 15</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">566</style></volume><pages><style face="normal" font="default" size="100%">1-7</style></pages><isbn><style face="normal" font="default" size="100%">1879-0038 (Electronic)0378-1119 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Muscle LIM Protein (MLP) has emerged as a key regulator of striated muscle physiology and pathophysiology. Mutations in cysteine and glycine-rich protein 3 (CSRP3), the gene encoding MLP, are causative of human cardiomyopathies, whereas altered expression patterns are observed in human failing heart and skeletal myopathies. In vitro and in vivo evidences reveal a complex and diverse functional role of MLP in striated muscle, which is determined by its multiple interacting partners and subcellular distribution. Experimental evidence suggests that MLP is implicated in both myogenic differentiation and myocyte cytoarchitecture, although the full spectrum of its intracellular roles still unfolds.</style></abstract><accession-num><style face="normal" font="default" size="100%">25936993</style></accession-num><notes><style face="normal" font="default" size="100%">Vafiadaki, ElizabethArvanitis, Demetrios ASanoudou, DespinaengU54 GM114833/GM/NIGMS NIH HHS/GM114833/GM/NIGMS NIH HHS/R01 GM089820/GM/NIGMS NIH HHS/R01 GM083924/GM/NIGMS NIH HHS/GM089820/GM/NIGMS NIH HHS/Research Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tReviewNetherlands2015/05/06 06:00Gene. 2015 Jul 15;566(1):1-7. doi: 10.1016/j.gene.2015.04.077. Epub 2015 Apr 30.</style></notes><custom2><style face="normal" font="default" size="100%">6660132</style></custom2><auth-address><style face="normal" font="default" size="100%">Molecular Biology Division, Biomedical Research Foundation of the Academy of Athens, Greece.Molecular Biology Division, Biomedical Research Foundation of the Academy of Athens, Greece; 4th Department of Internal Medicine, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Greece. Electronic address: dsanoudou@med.uoa.gr.</style></auth-address></record></records></xml>