@article {45902,
	title = {A cohort-based comprehensive characterization of different patterns of very short-term, within-visit, blood pressure variability.},
	journal = {Blood Press Monit},
	volume = {25},
	year = {2020},
	month = {2020 Jun},
	pages = {131-135},
	abstract = {AIM: To characterize different patterns of variability of three repeated within-visit blood pressure (BP) readings and to determine the prevalence of specific variation trends in systolic (SBP), diastolic (DBP) blood pressure and pulse pressure (PP).

METHODS: Data from 53 737 subjects from the National Health and Nutrition Examination Survey were analyzed. In each subject, three consecutive BP measurements were performed with a minimum time-interval of at least 30 s. We propose three patterns of within-visit BP variability (separately for SBP, DBP and PP): (1) increasing trend (BP3 > BP2 > BP1); (2) decreasing trend (BP1 > BP2 > BP3) and (3) no trend (BP3 ≈ BP2 ≈ BP1). A threshold of minimum change (ΔP > 3 mmHg) between BP1-BP2 and BP2-BP3 was also applied as a prerequisite for the definition of these trends.

RESULTS: An increasing trend was observed among three consecutive measurements of SBP, DBP and PP in 7.4, 10.4 and 10.2\%, respectively. When a minimum threshold of 3 mmHg was set the respective increasing trends were observed in 1.8, 2.9 and 4.4\%, respectively. There was a higher prevalence of decreasing trend within three consecutive SBP, DBP and PP readings: 17, 13.1 and 16.2\%, respectively, whereas using a threshold of ΔP >3 mmHg the respective prevalence was 6.3, 4.1 and 7.7\%. A maximum absolute difference >10 mmHg within triplicate of SBP/DBP/PP readings was observed in 12.9, 13 and 29.4\%, respectively. In the era of personalized medicine, these patterns are well worth further investigation concerning their pathophysiologic and clinical relevance.},
	keywords = {Blood Pressure, Blood Pressure Determination, Cohort Studies, Humans, Hypertension, Nutrition Surveys},
	issn = {1473-5725},
	doi = {10.1097/MBP.0000000000000435},
	author = {Papaioannou, Theodore G and Protogerou, Athanase D and Stamatelopoulos, Kimon S and Alexandraki, Krystallenia I and Vrachatis, Dimitrios and Argyris, Antonios and Papaioannou, Vasilios and Vavuranakis, Manolis and Stefanadis, Christodoulos and Tousoulis, Dimitrios}
}
