<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Giannopoulos, Georgios</style></author><author><style face="normal" font="default" size="100%">Kekeris, Vasileios</style></author><author><style face="normal" font="default" size="100%">Vrachatis, Dimitrios</style></author><author><style face="normal" font="default" size="100%">Kossyvakis, Charalampos</style></author><author><style face="normal" font="default" size="100%">Ntavelas, Charalampos</style></author><author><style face="normal" font="default" size="100%">Tsitsinakis, Georgios</style></author><author><style face="normal" font="default" size="100%">Koutivas, Athanasios</style></author><author><style face="normal" font="default" size="100%">Tolis, CHRISTOS</style></author><author><style face="normal" font="default" size="100%">Angelidis, Christos</style></author><author><style face="normal" font="default" size="100%">Deftereos, Spyridon</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of pulmonary vein isolation on left atrial appendage flow in paroxysmal atrial fibrillation.</style></title><secondary-title><style face="normal" font="default" size="100%">Pacing Clin Electrophysiol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Pacing Clin Electrophysiol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Atrial Appendage</style></keyword><keyword><style  face="normal" font="default" size="100%">Atrial Fibrillation</style></keyword><keyword><style  face="normal" font="default" size="100%">Cryosurgery</style></keyword><keyword><style  face="normal" font="default" size="100%">Echocardiography, Transesophageal</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Prospective Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Pulmonary Veins</style></keyword><keyword><style  face="normal" font="default" size="100%">Radiofrequency ablation</style></keyword><keyword><style  face="normal" font="default" size="100%">Treatment Outcome</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2018 Sep</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">41</style></volume><pages><style face="normal" font="default" size="100%">1129-1135</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">BACKGROUND: Left atrial appendage (LAA) functional modification in the context of pulmonary vein isolation has been a focus point of research and LAA emptying flow velocity (LAAEFV) is considered to reflect LAA contractility, stunning, and fibrosis.

OBJECTIVE: In the present study, we sought to prospectively evaluate short-term LAAEFV changes after radiofrequency (RF) or cryoballoon ablation in paroxysmal AF.

METHODS: This was a prospective substudy of the Effect of Cryoballoon and RF Ablation on Left Atrial Function (CryoLAEF) study (ClinicalTrials.gov Identifier: NCT02611869). Thirty patients, randomly assigned to RF or cryoablation, were prospectively followed. Transesophageal echocardiograms were performed at baseline and at 3 months postablation to measure LAAEFV.

RESULTS: All measurements were performed in sinus rhythm. Overall, LAAEFV was 44.2 [38.5-62.8] cm/s at baseline and was increased to 70.8 [64.8-77.6] cm/s at 3 months' postablation (P &lt; 0.001). Baseline LAAEFV was 52.5 [37.7-68.0] cm/s in the RF group and 42.8 [38.7-52.9] cm/s in the CryoBalloon group (P  =  0.653). At 3 months, the corresponding values were 68.5 [61.9-76.6] cm/s and 73.9 [69.2-79.9] cm/s, respectively (P  =  0.081 for the difference between the two groups at 3 months). The median change in LAAEFV was 11.0 [4.7-26.2] cm/s in the RF group versus 29.6 [15.8-37.0] cm/s in the CryoBalloon group (P  =  0.033).

CONCLUSION: LAA function is improved after catheter ablation with RF or balloon cryoablation in patients with paroxysmal AF, evaluated while in sinus rhythm both at baseline and on follow-up.</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/30028029?dopt=Abstract</style></custom1></record></records></xml>