<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vavuranakis, Manolis</style></author><author><style face="normal" font="default" size="100%">Kariori, Maria</style></author><author><style face="normal" font="default" size="100%">Scott, Lilly</style></author><author><style face="normal" font="default" size="100%">Kalogeras, Konstantinos</style></author><author><style face="normal" font="default" size="100%">Siasos, Gerasimos</style></author><author><style face="normal" font="default" size="100%">Vrachatis, Dimitrios</style></author><author><style face="normal" font="default" size="100%">Lavda, Maria</style></author><author><style face="normal" font="default" size="100%">Kalantzis, Charalampos</style></author><author><style face="normal" font="default" size="100%">Vavuranakis, Michael</style></author><author><style face="normal" font="default" size="100%">Bei, Evangelia</style></author><author><style face="normal" font="default" size="100%">Moldovan, Carmen-Maria</style></author><author><style face="normal" font="default" size="100%">Oikonomou, Evangelos</style></author><author><style face="normal" font="default" size="100%">Stefanadis, Christodoulos</style></author><author><style face="normal" font="default" size="100%">Tousoulis, Dimitrios</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Impact of &quot;high&quot; implantation on functionality of self-expandable bioprosthesis during the short- and long-term outcome of patients who undergo transcatheter aortic valve implantation: Is high implantation beneficial?</style></title><secondary-title><style face="normal" font="default" size="100%">Cardiovasc Ther</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Cardiovasc Ther</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Aged, 80 and over</style></keyword><keyword><style  face="normal" font="default" size="100%">Aortic valve</style></keyword><keyword><style  face="normal" font="default" size="100%">Aortic Valve Stenosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Bioprosthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">Coronary Vessels</style></keyword><keyword><style  face="normal" font="default" size="100%">Echocardiography</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Follow-Up Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Heart</style></keyword><keyword><style  face="normal" font="default" size="100%">Hemodynamics</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Prosthesis Implantation</style></keyword><keyword><style  face="normal" font="default" size="100%">Reproducibility of Results</style></keyword><keyword><style  face="normal" font="default" size="100%">Retrospective Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Tomography, X-Ray Computed</style></keyword><keyword><style  face="normal" font="default" size="100%">Transcatheter Aortic Valve Replacement</style></keyword><keyword><style  face="normal" font="default" size="100%">Treatment Outcome</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2018 Jun</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">36</style></volume><pages><style face="normal" font="default" size="100%">e12330</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">AIM: High position of the self-expandable bioprosthesis CoreValve/Evolut R has been proved to affect immediate hemodynamics of the valve. Whether this may have any impact on long-term procedural outcome has not been defined yet. The purpose of this study was to assess whether the final position of aortic bioprosthesis affects its long-term functionality.

METHOD: Consecutive patients (pts) who underwent successful TAVI procedure were evaluated and separated into 2 groups according to the implantation depth (ID): Group I: pts with 4 mm &lt;ID ≤13 mm; Group II: pts with ID ≤4 mm. ID was measured utilizing the final aortography after device delivery and was defined as the distance both from the native non- and left coronary cusp to the deepest edge of the deployed bioprosthesis in the left ventricle. Clinical outcome and echocardiographic parameters were recorded before the procedure, at discharge, at 1-month and 1-year-follow-up.

RESULTS: One hundred and ninety-eight pts (80 ± 5.5 years, 107 males [54%]) treated with the CoreValve/Evolut R bioprostheses were recorded. Group I appeared to have higher peak gradient (17 ± 6.5 vs 14 ± 5.5 mm Hg, P = .02) as well as Vmax (2 ± 0.4 vs 1.84 ± 0.38 m/s, P = .02) at follow-up after 1 year when compared with Group II (ID &lt;4 mm). Grouping for ID did not affect all-cause 1-year mortality. Paravalvular aortic regurgitation, as well as LVEF at discharge, proved to be independent predictors of all-cause 1-year mortality when adjusted for cofactors.

CONCLUSION: Implantation depth under 4 mm seems to have a favorable effect on long-term hemodynamic valve functionality.</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/29608814?dopt=Abstract</style></custom1></record></records></xml>