<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vavuranakis, Manolis</style></author><author><style face="normal" font="default" size="100%">Papaioannou, Theodore G</style></author><author><style face="normal" font="default" size="100%">Katsarou, Ourania A</style></author><author><style face="normal" font="default" size="100%">Vrachatis, Dimitrios A</style></author><author><style face="normal" font="default" size="100%">Elias A. Sanidas</style></author><author><style face="normal" font="default" size="100%">Siasos, Gerasimos</style></author><author><style face="normal" font="default" size="100%">Kalogeras, Konstantinos I</style></author><author><style face="normal" font="default" size="100%">Schizas, Dimitrios</style></author><author><style face="normal" font="default" size="100%">Stefanadis, Christodoulos I</style></author><author><style face="normal" font="default" size="100%">Tousoulis, Dimitris</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Impact of atherosclerotic plaque components and their distribution on stent deployment: an intravascular-ultrasound virtual histology observational study.</style></title><secondary-title><style face="normal" font="default" size="100%">Minerva Cardioangiol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Minerva Cardioangiol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Calcinosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Coronary Angiography</style></keyword><keyword><style  face="normal" font="default" size="100%">Coronary artery disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Cross-Sectional Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Percutaneous Coronary Intervention</style></keyword><keyword><style  face="normal" font="default" size="100%">Plaque, Atherosclerotic</style></keyword><keyword><style  face="normal" font="default" size="100%">Stents</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasonography, Interventional</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2016 Oct</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">64</style></volume><pages><style face="normal" font="default" size="100%">507-16</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">BACKGROUND: The aim of this study was to evaluate how the spatial distribution of each plaque element, defined by intravascular-ultrasound virtual histology (IVUS-VH), may affect stent deployment even at high inflation pressures.

METHODS: Thirty-two patients undergoing direct percutaneous coronary intervention and IVUS were evaluated. Fifty-two lesions were treated with drug-eluting stents. Pre-stenting lumen area and real (Rcssla) and average cross-sectional stent lumen area (Acssla) were measured along the whole lesion. Ideal cross-sectional stent lumen area (Icssla) was calculated. Plaque composition was characterized by IVUS-VH. The spatial distribution of each plaque element was quantified by a novel image analysis tool measuring the area and percentage of each plaque component that was adjacent to the lumen. Average stent deployment was defined as: [1 - (Icssla-Acssla)/Icssla]×100%.

RESULTS: Stent expansion was significantly less at the site of maximum calcification compared to the average stent deployment (80±9% vs. 85±13%, P=0.044, respectively). Furthermore, wherever calcium was adjacent to the lumen, stent expansion was impaired compared to sites where calcium was non-luminal (70±23% vs. 80±9%, P=0.01, respectively). In contrast, at the site of maximum necrotic core, stent deployment showed a trend to be less compromised, compared to the average stent deployment.

CONCLUSIONS: An interaction was found between plaque components and their distribution and stent deployment even at high inflation pressures.</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/26080685?dopt=Abstract</style></custom1></record></records></xml>