@article {Bogdanis1996876,
	title = {Contribution of phosphocreatine and aerobic metabolism to energy supply during repeated sprint exercise},
	journal = {Journal of Applied Physiology},
	volume = {80},
	number = {3},
	year = {1996},
	note = {cited By 296},
	pages = {876-884},
	abstract = {This study examined the contribution of phosphocreatine (PCr) and aerobic metabolism during repeated bouts of sprint exercise. Eight male subjects performed two cycle ergometer sprints separated by 4 min of recovery during two separate main trials. Sprint 1 lasted 30 s during both main trials, whereas sprint 2 lasted either 10 or 30 s. Muscle biopsies were obtained at rest, immediately after the first 30-s sprint, after 3.8 min of recovery, and after the second 10-and 30-s sprints. At the end of sprint 1, PCr was 16.9 {\textpm} 1.4\% of the resting value, and muscle pH dropped to 6.69 {\textpm} 0.02. After 3.8 min of recovery, muscle pH remained unchanged (6.80 {\textpm} 0.03), but PCr was resynthesized to 78.7 {\textpm} 3.3\% of the resting value. PCr during sprint 2 was almost completely utilized in the first 10 s and remained unchanged thereafter. High correlations were found between the percentage of PCr resynthesis and the percentage recovery of power output and pedaling speed during the initial 10 s of sprint 2 (r = 0.84, P < 0.05 and r = 0.91, P < 0.01). The anaerobic ATP turnover, as calculated from changes in ATP, PCr, and lactate, was 235 {\textpm} 9 mmol/kg dry muscle during the first sprint but was decreased to 139 {\textpm} 7 mmol/kg dry muscle during the second 30-s sprint, mainly as a result of a ~45\% decrease in glycolysis. Despite this ~41\% reduction in anaerobic energy, the total work done during the second 30-s sprint was reduced by only ~18\%. This mismatch between anaerobic energy release and power output during sprint 2 was partly compensated for by an increased contribution of aerobic metabolism, as calculated from the increase in oxygen uptake during sprint 2 (2.68 {\textpm} 0.10 vs. 3.17 {\textpm} 0.13 l/min; sprint 1 vs. sprint 2; P < 0.01). These data suggest that aerobic metabolism provides a significant part (~49\%) of the energy during the second sprint, whereas PCr availability is important for high power output during the initial 10 s.},
	url = {https://www.scopus.com/inward/record.url?eid=2-s2.0-0029986417\&partnerID=40\&md5=355aac30b04cf97f0864a36c4c7207e5},
	author = {Bogdanis, G.C. and Nevill, M.E. and Boobis, L.H. and Lakomy, H.K.A.}
}
