@article {5155,
	title = {Molecular analysis of the carbapenem and metronidazole resistance mechanisms of Bacteroides strains reported in a Europe-wide antibiotic resistance survey.},
	journal = {Int J Antimicrob Agents},
	volume = {41},
	year = {2013},
	month = {2013 Feb},
	pages = {122-5},
	abstract = {Here we examine the carbapenem and metronidazole resistance mechanisms of 640 Bacteroides strains reported in the 2008-2009 European antibiotic susceptibility survey. Of the 22 strains with elevated imipenem minimum inhibitory concentrations (>=4 μg/mL), 10 were cfiA-positive and out of these 5 carried activating insertion sequence (IS) elements in the upstream regions of the cfiA genes. However, resistant strains with cfiA genes but with no activating IS elements were found (n=2) as well as a resistant strain with no cfiA gene. In the former the resistance phenotypes by Etest were heterogeneous, whilst in the latter no carbapenemase production was seen; both mechanisms have been rarely observed, examined and characterised. Interestingly, few (n=3) nim-positive strains were found, including one metronidazole-resistant strain harbouring nimE activated by ISBf6, and two susceptible strains harbouring chromosomally located nim genes.},
	keywords = {Anti-Bacterial Agents, Bacterial Proteins, Bacteroides, Bacteroides Infections, Carbapenems, DNA Transposable Elements, DNA, Bacterial, Drug Resistance, Bacterial, Europe, Humans, Metronidazole, Microbial Sensitivity Tests, Molecular Sequence Data, Sequence Analysis, DNA},
	issn = {1872-7913},
	doi = {10.1016/j.ijantimicag.2012.10.001},
	author = {S{\'o}ki, J{\'o}zsef and Eitel, Zsuzsa and Urb{\'a}n, Edit and Nagy, Elisabeth}
}
