<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Papapanagiotou, I.K.</style></author><author><style face="normal" font="default" size="100%">Charamanta, M.</style></author><author><style face="normal" font="default" size="100%">Roidi, S.</style></author><author><style face="normal" font="default" size="100%">Al-Achmar, N.S.</style></author><author><style face="normal" font="default" size="100%">Soldatou, A.</style></author><author><style face="normal" font="default" size="100%">Michala, L.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">{The Use of Norethisterone for the Treatment of Severe Uterine Bleeding in Adolescents: An Audit of Our Experience}</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Pediatric and Adolescent Gynecology</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Abnormal uterine bleeding</style></keyword><keyword><style  face="normal" font="default" size="100%">Adolescents</style></keyword><keyword><style  face="normal" font="default" size="100%">AUB</style></keyword><keyword><style  face="normal" font="default" size="100%">Heavy menstrual bleeding</style></keyword><keyword><style  face="normal" font="default" size="100%">norethisterone</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year></dates><number><style face="normal" font="default" size="100%">6</style></number><volume><style face="normal" font="default" size="100%">32</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">© 2019 North American Society for Pediatric and Adolescent Gynecology Study Objective: The purpose of this prospective study was to assess the effectiveness of norethisterone (NET) in the management of abnormal uterine bleeding (AUB) in adolescents in a tertiary care center. Design: This was a prospective audit focused on administering high doses of NET in female adolescents with complaints of AUB. Setting: We included female adolescents who presented to our Emergency Gynecological Department or Adolescent Gynecological Outpatient Department from October 2016 to January 2019. Participants: The study included 29 female adolescents aged 11-17 (mean, 13.14) years. Interventions: Patients were administered a daily dose of 10-30 mg, depending on the severity of the condition, bleeding duration, and patient weight. Main Outcome Measures: Cessation of vaginal bleeding. Results: Mean age at menarche of our patient sample was 11.4 years (range, 10.7-14 years). AUB presented at a mean time of 24.6 months after menarche (range, 0-79 months). Blood transfusion was deemed necessary in 9 patients. Bleeding stopped at a mean of 46.1 (range, 8-120) hours after onset of treatment with NET. No serious adverse events were reported with NET administration, with only 3 cases of minor side effects. Conclusion: The use of NET is an effective and reliable treatment option among adolescents for whom control of AUB is desired in the acute setting.</style></abstract></record></records></xml>