@article { WOS:A1994NT17300005,
	title = {AUTOMATED FLOW-INJECTION TECHNIQUE FOR USE IN DISSOLUTION STUDIES OF SUSTAINED-RELEASE FORMULATIONS - APPLICATION TO IRON(II) FORMULATIONS},
	journal = {JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS},
	volume = {12},
	number = {5},
	year = {1994},
	month = {MAY},
	pages = {635-641},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB},
	abstract = {The application of flow-injection analysis (FIA) to automated dissolution studies of sustained-release formulations is described. The long-term stability of the dissolution-FIA analyser was checked during unattended operation for 42 h. The construction of multiple calibration curves with the so-called electronic dilution FIA procedure was used to extend the linear range of the determination. The computer-controlled FIA system and the principles of associated software are described and applied to dissolution studies of sustained-release formulations of iron(II) using its sensitive reaction with the colour reagent, ferrozine. The extended linear range of the determination is 1-130 ppm iron(II) and the precision (RSD) better than 3\% (n = 3).},
	keywords = {DISSOLUTION TESTING AUTOMATION, FERROZINE, FLOW-INJECTION ANALYSIS, IRON DETERMINATION IN DRUG FORMULATIONS, SUSTAINED-RELEASE FORMULATIONS},
	issn = {0731-7085},
	doi = {10.1016/0731-7085(93)E0015-F},
	author = {Georgiou, C.A. and Valsami, GN and Macheras, PE and Koupparis, MA}
}
