@article {10164,
	title = {Fetuin-A levels and free leptin index are reduced in patients with chronic lymphocytic leukemia: a hospital-based case-control study.},
	journal = {Leuk Lymphoma},
	volume = {57},
	year = {2016},
	month = {2016},
	pages = {577-84},
	abstract = {There are limited data on fetuin-A, soluble leptin receptor (sOB-R) and free leptin index (FLI) in patients with chronic lymphocytic leukemia (CLL). The aim of this study was to compare circulating fetuin-A, sOB-R levels and FLI between 95 patients with CLL and 95 matched controls, as well as among different stages of CLL. Circulating fetuin-A was significantly lower in cases than controls (241.9 {\textpm} 99.2 vs. 288.8 {\textpm} 127.7 μg/mL; p = 0.005). Although circulating sOB-R levels were similar between groups, FLI was lower in cases than controls (0.45 {\textpm} 0.42 vs. 0.67 {\textpm} 0.57; p = 0.003). Furthermore, lower fetuin-A or FLI, but not sOB-R, were independently associated with CLL (p < 0.05), particularly among overweight/obese individuals. Fetuin-A, s-OB-R and FLI were similar between different stages of CLL severity, or between symptomatic and asymptomatic disease. In conclusion, circulating fetuin-A and FLI, but not sOB-R, were lower in patients with CLL than controls, a finding warranting further investigation.},
	keywords = {Aged, alpha-2-HS-Glycoprotein, Biomarkers, Case-Control Studies, Female, Humans, Leptin, Leukemia, Lymphocytic, Chronic, B-Cell, Male, Middle Aged, Neoplasm Staging, Odds Ratio, Prognosis, Risk Factors},
	issn = {1029-2403},
	doi = {10.3109/10428194.2015.1075523},
	author = {Dalamaga, Maria and Polyzos, Stergios A and Karmaniolas, Konstantinos and Chamberland, John and Lekka, Antigoni and Triantafilli, Maria and Migdalis, Ilias and Papadavid, Evangelia and Mantzoros, Christos S}
}
