@article {10168,
	title = {Association of clinicopathological characteristics with secondary neoplastic lymphoproliferative disorders in patients with lymphomatoid papulosis.},
	journal = {Leuk Lymphoma},
	volume = {56},
	year = {2015},
	month = {2015 May},
	pages = {1303-7},
	abstract = {Lymphomatoid papulosis (LyP) refers to an indolent cutaneous lymphoma. The association of prognostic clinicopathological risk factors with a second hematologic malignancy has not yet been determined. We investigated the prognostic effect of clinicopathological characteristics on the occurrence of a second lymphoma, as well as the first-line treatment, in 24 patients diagnosed with LyP using logistic regression models. We showed that lymphoma occurrence was associated with a lower mean age at onset of LyP symptoms, histological types B and C, head-located LyP lesions and a higher frequency of LyP recurrences. In multivariate analyses, histologic type A was associated with a lower risk of second lymphoma (odds ratio [OR] = 0.12, 95\% confidence interval [CI] 0.014-0.98; p = 0.045) adjusting for age of LyP first symptomatology, and an important increased lymphoma-free survival rate (long-rank test; p = 0.06). Clinicopathological characteristics are important in defining the clearance or persistence of LyP lesions and may predict the occurrence of a second lymphoma.},
	keywords = {Adult, Aged, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Lymphomatoid Papulosis, Lymphoproliferative Disorders, Male, Middle Aged, Neoplasms, Second Primary, Odds Ratio, Recurrence, Skin Neoplasms, Time Factors, Young Adult},
	issn = {1029-2403},
	doi = {10.3109/10428194.2014.958821},
	author = {Nikolaou, Vassiliki and Papadavid, Evangelia and Ekonomidi, Afroditi and Dalamaga, Maria and Marinos, Leonidas and Stratigos, Alexandros and Papadaki, Theodora and Antoniou, Christina}
}
