@article {10189,
	title = {Lobomycosis: A case from Southeastern Europe and review of the literature.},
	journal = {J Dermatol Case Rep},
	volume = {6},
	year = {2012},
	month = {2012 Sep 28},
	pages = {65-9},
	abstract = {BACKGROUND: Lobomycosis, also known as Jorge Lobo{\textquoteright}s disease, represents a rare chronic subcutaneous mycosis caused by the fungus Lacazia loboi, an organism that is found within lesions but has not been cultured to date. The natural reservoir of L. loboi is unknown but it is believed to be aquatic, or associated with soil and vegetation. More than 550 human cases have been reported, especially in patients with a history of travel or residence in endemic areas (Central and South America, particularly Brazil) or in communities along rivers.

MAIN OBSERVATIONS: We describe a 64-year-old Greek female farmer living in a coastal region, who presented with an erythematous plaque on her left inner thigh resembling a keloid. The diagnosis was based on the triad: 1) absence of fungal growth in cultures, 2) positive direct microscopic examination of the lesion and 3) histopathology, all consistent with lobomycosis. Particularly, skin biopsy showed deep cutaneous fungal infection with granulomatous reaction. Fungal cells were found inside giant cells. The fungi were thick-walled with some budding, isolated or in short chains. Dermal fibrosis was present. Our patient had a medical history of common variable immunodeficiency but no history of travel to South or Central America. She probably acquired this rare infection by injury during her agricultural works.

CONCLUSION: Our case represents probably the first documented case of human lobomycosis in Southeastern Europe. This case is unusual due to the rarity of lobomycosis in Mediterranean countries, particularly in Southeastern Europe.},
	issn = {1898-7249},
	doi = {10.3315/jdcr.2012.1104},
	author = {Papadavid, Evangelia and Dalamaga, Maria and Kapniari, Irini and Pantelidaki, Ekaterini and Papageorgiou, Sotirios and Pappa, Vassiliki and Tsirigotis, Panagiotis and Dervenoulas, Ioannis and Stavrianeas, Nikolaos and Rigopoulos, Dimitrios}
}
