@article {44688,
	title = {Cancer quiescence: non-coding RNAs in the spotlight},
	journal = {Trends in Molecular Medicine},
	volume = {29},
	number = {10},
	year = {2023},
	note = {Soureas, KonstantinosPapadimitriou, Maria-AlexandraPanoutsopoulou, KonstantinaPilala, Katerina-MarinaScorilas, AndreasAvgeris, MargaritisengResearch Support, Non-U.S. Gov{\textquoteright}tReviewEngland2023/07/30 01:06Trends Mol Med. 2023 Oct;29(10):843-858. doi: 10.1016/j.molmed.2023.07.003. Epub 2023 Jul 27.},
	month = {Oct},
	pages = {843-858},
	abstract = {Cancer quiescence reflects the ability of cancer cells to enter a reversible slow-cycling or mitotically dormant state and represents a powerful self-protecting mechanism preventing cancer cell {\textquoteright}damage{\textquoteright} from hypoxic conditions, nutrient deprivation, immune surveillance, and (chemo)therapy. When stress conditions are restrained, and tumor microenvironment becomes beneficial, quiescent cancer cells re-enter cell cycle to facilitate tumor spread and cancer progression/metastasis. Recent studies have highlighted the dynamic role of regulatory non-coding RNAs (ncRNAs) in orchestrating cancer quiescence. The elucidation of regulatory ncRNA networks will shed light on the quiescence-proliferation equilibrium and, ultimately, pave the way for new treatment options. Herein, we have summarized the ever-growing role of ncRNAs upon cancer quiescence regulation and their impact on treatment resistance and modern cancer therapeutics.},
	keywords = {*Neoplasms/genetics/therapy/pathology, *RNA, Long Noncoding/genetics, cancer dormancy, cancer quiescence, Cell Division, chemoresistance, Humans, long non-coding RNAs, miRNAs, RNA, Untranslated/genetics, this article., tumor microenvironment, Tumor Microenvironment/genetics},
	isbn = {1471-499X (Electronic)1471-4914 (Linking)},
	author = {Soureas, K. and Papadimitriou, M. A. and Panoutsopoulou, K. and Pilala, K. M. and Scorilas, A. and Avgeris, M.}
}
