<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Soureas, K.</style></author><author><style face="normal" font="default" size="100%">Papadimitriou, M. A.</style></author><author><style face="normal" font="default" size="100%">Panoutsopoulou, K.</style></author><author><style face="normal" font="default" size="100%">Pilala, K. M.</style></author><author><style face="normal" font="default" size="100%">Scorilas, A.</style></author><author><style face="normal" font="default" size="100%">Avgeris, M.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cancer quiescence: non-coding RNAs in the spotlight</style></title><secondary-title><style face="normal" font="default" size="100%">Trends in Molecular Medicine</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">*Neoplasms/genetics/therapy/pathology</style></keyword><keyword><style  face="normal" font="default" size="100%">*RNA, Long Noncoding/genetics</style></keyword><keyword><style  face="normal" font="default" size="100%">cancer dormancy</style></keyword><keyword><style  face="normal" font="default" size="100%">cancer quiescence</style></keyword><keyword><style  face="normal" font="default" size="100%">Cell Division</style></keyword><keyword><style  face="normal" font="default" size="100%">chemoresistance</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">long non-coding RNAs</style></keyword><keyword><style  face="normal" font="default" size="100%">miRNAs</style></keyword><keyword><style  face="normal" font="default" size="100%">RNA, Untranslated/genetics</style></keyword><keyword><style  face="normal" font="default" size="100%">this article.</style></keyword><keyword><style  face="normal" font="default" size="100%">tumor microenvironment</style></keyword><keyword><style  face="normal" font="default" size="100%">Tumor Microenvironment/genetics</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">10</style></number><volume><style face="normal" font="default" size="100%">29</style></volume><pages><style face="normal" font="default" size="100%">843-858</style></pages><isbn><style face="normal" font="default" size="100%">1471-499X (Electronic)1471-4914 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Cancer quiescence reflects the ability of cancer cells to enter a reversible slow-cycling or mitotically dormant state and represents a powerful self-protecting mechanism preventing cancer cell 'damage' from hypoxic conditions, nutrient deprivation, immune surveillance, and (chemo)therapy. When stress conditions are restrained, and tumor microenvironment becomes beneficial, quiescent cancer cells re-enter cell cycle to facilitate tumor spread and cancer progression/metastasis. Recent studies have highlighted the dynamic role of regulatory non-coding RNAs (ncRNAs) in orchestrating cancer quiescence. The elucidation of regulatory ncRNA networks will shed light on the quiescence-proliferation equilibrium and, ultimately, pave the way for new treatment options. Herein, we have summarized the ever-growing role of ncRNAs upon cancer quiescence regulation and their impact on treatment resistance and modern cancer therapeutics.</style></abstract><accession-num><style face="normal" font="default" size="100%">37516569</style></accession-num><notes><style face="normal" font="default" size="100%">Soureas, KonstantinosPapadimitriou, Maria-AlexandraPanoutsopoulou, KonstantinaPilala, Katerina-MarinaScorilas, AndreasAvgeris, MargaritisengResearch Support, Non-U.S. Gov'tReviewEngland2023/07/30 01:06Trends Mol Med. 2023 Oct;29(10):843-858. doi: 10.1016/j.molmed.2023.07.003. Epub 2023 Jul 27.</style></notes><auth-address><style face="normal" font="default" size="100%">Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece; Laboratory of Clinical Biochemistry - Molecular Diagnostics, Second Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, 'P. &amp; A. Kyriakou' Children's Hospital, Athens, Greece.Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece; Laboratory of Clinical Biochemistry - Molecular Diagnostics, Second Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, 'P. &amp; A. Kyriakou' Children's Hospital, Athens, Greece. Electronic address: mavgeris@med.uoa.gr.</style></auth-address></record></records></xml>