@article {7519,
	title = {Overall survival of relapsed and refractory multiple myeloma patients after adjusting for crossover in the MM-003 trial for pomalidomide plus low-dose dexamethasone},
	journal = {British Journal of Haematology},
	volume = {168},
	year = {2015},
	note = {Cited By :7Export Date: 21 February 2017},
	month = {2015},
	pages = {820 - 823},
	abstract = {Summary: In the phase III MM-003 trial, pomalidomide plus low-dose dexamethasone (POM+LoDEX) improved overall survival (OS) versus high-dose dexamethasone (HiDEX) in 455 patients with relapsed and refractory multiple myeloma (RRMM) after treatment with bortezomib and lenalidomide. Here, a two-stage Weibull method was used to adjust for the crossover of patients in the HiDEX arm to pomalidomide-based therapy. The adjusted difference in median OS between patients in the POM+LoDEX and HiDEX arms was 7{\textperiodcentered}0 months (12{\textperiodcentered}7 vs. 5{\textperiodcentered}7 months, respectively). These findings provide important evidence for understanding the clinical efficacy of pomalidomide on OS benefits seen in RRMM patients. {\textcopyright} 2014 John Wiley \& Sons Ltd.},
	keywords = {Bias, Crossover, multiple myeloma, pomalidomide, Survival},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84924034402\&doi=10.1111\%2fbjh.13227\&partnerID=40\&md5=01fe15c81825e4a7d834d4b9cdee3ca3},
	author = {Morgan, G. and Palumbo, A. and Dhanasiri, S. and Lee, D. and Weisel, K. and Facon, T. and Delforge, M. and Oriol, A. and Zaki, M. and Yu, X. and Sternas, L. and Jacques, C. and Akehurst, R. and Offner, F. and Dimopoulos, M.A.}
}
