@article {7593,
	title = {MMP-2 -1306C > T polymorphism in breast cancer: A case-control study in a South European population},
	journal = {Molecular Biology Reports},
	volume = {40},
	year = {2013},
	note = {Cited By :2Export Date: 21 February 2017},
	month = {2013},
	pages = {5035 - 5040},
	abstract = {This case control study aims to investigate the role of MMP-2 -1306C > T polymorphism as a potential risk factor and possible prognostic marker for breast cancer in a South European population. 113 consecutive incident cases of histologically confirmed ductal breast cancer and 124 healthy controls were recruited. MMP-2 -1306C > T polymorphism was genotyped; multivariate logistic regression as well as Cox regression analysis were performed. MMP-2 -1306C > T status was not associated with breast cancer risk either at the total sample or at the subanalyses on premenopausal and postmenopausal women. At the survival analysis, a trend towards a favorable association between MMP-2 -1306C > T allele and disease-free survival as well as overall survival was observed. Regarding subanalyses on ER-negative and ER-positive cases, the favorable association implicating MMP-2 -1306C > T allele was particularly evident among ER-positive cases; no significant associations emerged among ER-negative cases. MMP-2 -1306C > T polymorphism does not seem to be a risk factor for breast cancer in South European population; however, a trend towards a favorable association with survival has been observed. {\textcopyright} 2013 Springer Science+Business Media Dordrecht.},
	keywords = {breast cancer, Case control, MMP-2, MMP-2 -1306C > T polymorphism, Polymorphism},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84881124597\&doi=10.1007\%2fs11033-013-2604-5\&partnerID=40\&md5=f3a91b39f25445a1e4243dbd725f517a},
	author = {Zagouri, F. and Sergentanis, T.N. and Gazouli, M. and Dimitrakakis, C. and Tsigginou, A. and Papaspyrou, I. and Chrysikos, D. and Lymperi, M. and Zografos, G.C. and Antsaklis, A. and Dimopoulos, M.-A. and Papadimitriou, C.A.}
}
