@article {7735,
	title = {Report of the long-term efficacy of two cycles of adjuvant bleomycin/etoposide/cisplatin in patients with stage I testicular nonseminomatous germ-cell tumors (NSGCT): A risk adapted protocol of the Hellenic Cooperative Oncology Group},
	journal = {Urologic Oncology: Seminars and Original Investigations},
	volume = {29},
	year = {2011},
	note = {Cited By :6Export Date: 21 February 2017},
	month = {2011},
	pages = {189 - 193},
	abstract = {Objectives: Stage I testicular nonseminomatous germ-cell tumors (NSGCT) are highly curable. Following orchidectomy surveillance, adjuvant chemotherapy and retroperitoneal lymph node dissection can be applied. Certain factors are used to select patients in high-risk for relapse. We report the outcome and safety of a risk-adapted strategy by the Hellenic Cooperative Oncology Group. Methods: Between 1994 and 2004, 142 patients with stage I NSGCT and 1 of the following risk factors: lymphovascular invasion (LVI), invasion of tunica vaginalis, spermatic cord, rete testis or scrotal wall, embryonal component \&gt;50\% of the total tumor, were prospectively included in a protocol of adjuvant chemotherapy consisting of two 3-week courses of bleomycin 15 IU, etoposide 120 mg/m2, and cisplatin 40 mg/m2 for 3 consecutive days with G-CSF support. Results: Median follow-up was 79 months and 138 patients have been followed for at least 2 years. Seventy-seven patients (54\%) had LVI and 74 (52\%) had \&gt;50\% embryonal component. There was 1 relapse, which was cured with chemotherapy and surgery. Another patient died due to disease-unrelated causes and 1 patient developed a new primary of the remaining testicle, which was cured with surgery. Conclusion: Two cycles of bleomycin/etoposide/cisplatin is an effective and safe form of adjuvant therapy in high-risk stage I NSGCT. {\textcopyright} 2011 Elsevier Inc.},
	keywords = {BEP, Chemotherapy, Nonseminoma, Stage I},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952038488\&doi=10.1016\%2fj.urolonc.2009.01.017\&partnerID=40\&md5=880f1e9d4a90a930864e162dc5111da6},
	author = {Bamias, A. and Aravantinos, G. and Kastriotis, I. and Alivizatos, G. and Anastasiou, I. and Christodoulou, C. and Gyftaki, R. and Kalofonos, H.P. and Dimopoulos, M.A.}
}
