@article {7820,
	title = {Clinicopathological features of primary fallopian tube carcinoma: A single institution experience},
	journal = {European Journal of Gynaecological Oncology},
	volume = {30},
	year = {2009},
	note = {Cited By :5Export Date: 21 February 2017},
	month = {2009},
	pages = {389 - 395},
	abstract = {Purpose of investigation: Primary fallopian tube carcinoma (PFTC) is a rare malignancy with only few data existing on the impact of prognostic factors. Methods: We retrospectively analyzed 26 patients. Tissue blocks were reviewed and sections were stained for vascular endothelial growth factor (VEGF), matrix metalloproteinases 2 and 9 (MMP-2, MMP-9), tissue inhibitors of metalloproteinases 1 and 2 (TIMP-1, TIMP-2), c-erbB-2, estrogen (ER), and progesterone receptors (PgR). Results: Reactivity for VEGF, ER, PgR, MMP-2, MMP-9, TIMP-1, TIMP-2 and c-erbB-2 was observed in 85\%, 46\%, 27\%, 11.5\%, 58\%, 0\%, 23\% and 8\% of specimens, respectively. None of the markers studied displayed prognostic significance. Regarding clinical prognostic factors, the hazard ratio (HR) for progression and death for patients with tumor residuum > 2 cm was 5.24 (p < 0.01) and 11.19 (p < 0.005), respectively. Patients with advanced stage disease had a HR of 12.55 (p < 0.05) for progression, while the HR for death was not found to be statistically significant. Conclusion: None of the biomarkers studied seems to influence survival. Early-stage disease and optimal debulking are associated with improved outcome.},
	keywords = {First-line chemotherapy, Immunohistochemistry, Primary fallopian tube cancer, Prognostic factors},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-68849105112\&partnerID=40\&md5=cbf7cfaf0083364f1e301970e7bb6050},
	author = {Papadimitriou, C.A. and Markaki, S. and Lianos, E. and Peitsidis, P. and Vourli, G. and Nikitas, N. and Vlachos, G. and Rodolakis, A. and Antsaklis, A. and Dimopoulos, M.A.}
}
