@article {7992,
	title = {The outcome of advanced or recurrent non-squamous carcinoma of the uterine cervix after platinum-based combination chemotherapy},
	journal = {Gynecologic Oncology},
	volume = {99},
	year = {2005},
	note = {Cited By :24Export Date: 21 February 2017},
	month = {2005},
	pages = {376 - 382},
	abstract = {Background. Data about the outcome and prognostic factors in the group of patients with non-squamous cell advanced or recurrent carcinomas of the uterine cervix are limited. We compared the outcome of patients with non-squamous with that of squamous cell carcinomas after platinum-based combination chemotherapy as first line therapy for stage IV or recurrent cervical carcinoma. Patients and methods. A total of 200 patients with stage IV or recurrent carcinomas of the cervix received platinum-based combination chemotherapy and were included in our analysis. Results. There were 58 patients with non-squamous and 142 patients with squamous cell carcinomas. Response to chemotherapy was 53.5\% in non-squamous vs. 43.5\% in squamous carcinomas. Histology was not an independent predictor of tumor response (P = 0.797). Response rates were lower in patients with relapse only in a previously irradiated area in both squamous (26.9\% vs. 53.5\%, P = 0.005) and non-squamous carcinomas (47.1\% vs. 65\%, P = 0.270). Weight loss was the only significant predictor of survival in non-squamous histology patients (P <0.0001). There was no significant difference in median survival between squamous (11.57 months [95\% CI 9.35-13.79]) and non-squamous carcinomas (19.05 months [95\% CI 13.63-24.47]) (P = 0.064). After adjustment for independent prognostic factors (ECOG performance status and weight loss), differences in survival remained not significant. Conclusion. Our study showed a similar outcome for both squamous and non-squamous stage IV or recurrent cervical carcinomas treated with platinum-based combination chemotherapy. {\textcopyright} 2005 Elsevier Inc. All rights reserved.},
	keywords = {Cervical cancer, Chemotherapy, Non-squamous, Platinum, Recurrent},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-27144547596\&doi=10.1016\%2fj.ygyno.2005.06.024\&partnerID=40\&md5=bd53b96c9ece45b1bf2dcd7fc8a4b370},
	author = {Kastritis, E. and Bamias, A. and Efstathiou, E. and Gika, D. and Bozas, G. and Zorzou, P. and Sarris, K. and Papadimitriou, C. and Dimopoulos, M.A.}
}
