@article {8114,
	title = {The significance of PSA/IGF-1 ratio in differentiating benign prostate hyperplasia from prostate cancer},
	journal = {Disease Markers},
	volume = {16},
	year = {2000},
	note = {Cited By :6Export Date: 21 February 2017},
	month = {2000},
	pages = {143 - 146},
	abstract = {The importance of insulin-like growth factor 1 (IGF-1) in human serum for the early diagnosis of prostate cancer is controversial. The IGF-1/PSA ratio may improve the performance of prostate specific antigen (PSA) as a prostate cancer marker. IGF-1, along with PSA and free PSA concentration, was measured in the serum of 34 patients with prostate cancer and in 131 patients with benign prostatic hyperplasia (BPH). Although IGF-1 concentration did not significantly differ between the groups, PSA/IGF-1 ratio could clearly distinguish the two groups. In patients with cancer but not in patients with BPH, IGF-1 concentration correlated with PSA and free PSA. The values of PSA and free PSA correlated with each other for both groups. Receivers Operating Curve (ROC) analysis indicated a better sensitivity to specificity ratio for PSA/IGF-1 than for PSA or Free/Total (F/T) PSA.},
	keywords = {IGF-1, Prostate cancer, Prostatic hypertrophy, PSA},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034437042\&partnerID=40\&md5=16781c7ba9b3a5f84b8130040157d3c1},
	author = {Koliakos, G. and Chatzivasiliou, D. and Dimopoulos, Th. and Trachana, V. and Paschalidou, K. and Galiamoutsas, V. and Triantos, A. and Chitas, G. and Dimopoulos, A. and Vlatsas, G.}
}
