<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hajek, R.</style></author><author><style face="normal" font="default" size="100%">Siegel, D.</style></author><author><style face="normal" font="default" size="100%">Orlowski, R.Z.</style></author><author><style face="normal" font="default" size="100%">Ludwig, H.</style></author><author><style face="normal" font="default" size="100%">Palumbo, A.</style></author><author><style face="normal" font="default" size="100%">Dimopoulos, M.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The role of histone deacetylase inhibitors in patients with relapsed/refractory multiple myeloma</style></title><secondary-title><style face="normal" font="default" size="100%">Leukemia and Lymphoma</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">bortezomib</style></keyword><keyword><style  face="normal" font="default" size="100%">Histone deacetylase inhibitor</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunomodulatory drug</style></keyword><keyword><style  face="normal" font="default" size="100%">multiple myeloma</style></keyword><keyword><style  face="normal" font="default" size="100%">proteasome inhibitor</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2014</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891365148&amp;doi=10.3109%2f10428194.2013.797084&amp;partnerID=40&amp;md5=574b2716387a7349f5c98f4fb7ad5683</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">55</style></volume><pages><style face="normal" font="default" size="100%">11 - 18</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Clinical outcomes for patients with multiple myeloma (MM) have improved substantially since the introduction of novel agents including the proteasome inhibitor bortezomib and the immunomodulatory drugs thalidomide and lenalidomide. However, most patients with MM eventually relapse, and prognosis remains poor among patients with relapsed and/or refractory disease. Combination therapy using agents with different mechanisms of action is emerging as an attractive treatment approach in oncology to increase efficacy and/or overcome resistance to standard treatment regimens. This review discusses unmet needs in the treatment of MM and the development of histone deacetylase inhibitors as a treatment modality for MM. © 2013 Informa UK, Ltd.</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><notes><style face="normal" font="default" size="100%">Cited By :4Export Date: 21 February 2017</style></notes></record></records></xml>