<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Alexanian, R.</style></author><author><style face="normal" font="default" size="100%">Dimopoulos, M.A.</style></author><author><style face="normal" font="default" size="100%">Delasalle, K.B.</style></author><author><style face="normal" font="default" size="100%">Hester, J.</style></author><author><style face="normal" font="default" size="100%">Champlin, R.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Myeloablative therapy for primary resistant multiple myeloma</style></title><secondary-title><style face="normal" font="default" size="100%">STEM CELLS</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Autologous marrow</style></keyword><keyword><style  face="normal" font="default" size="100%">Autologous stem cells</style></keyword><keyword><style  face="normal" font="default" size="100%">Early therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Late therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">multiple myeloma</style></keyword><keyword><style  face="normal" font="default" size="100%">Myeloablative therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Primary resistance</style></keyword><keyword><style  face="normal" font="default" size="100%">Survival</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1995</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1995</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029096150&amp;doi=10.1002%2fstem.5530130718&amp;partnerID=40&amp;md5=a47ab137d03224a583d65808d42184c4</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">118 - 121</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Myeloablative therapy supported by autologous bone marrow or blood stem cell transplantation was assessed in 41 patients who had multiple myeloma resistant to vincristine‐doxorubicin by continuous infusion with high‐dose dexamethasone (VAD) or other high‐dose dexamethasone regimens. In patients who had high or intermediate tumor mass, the myeloma cell mass was reduced by more than 75% in 56% of patients and the survival time quadrupled in comparison with that of a matched control group. Later treatment resulted in a lower response rate and shorter remission. Current myeloablative regimens supported by autologous stem cells provided a useful treatment for patients who had advanced primary resistant multiple myeloma. Such treatment should be given early in the disease course to provide the best chance for remission, collecting blood stem cells with facility, and preventing complications that would increase the risk of the procedure. Copyright © 1995 AlphaMed Press</style></abstract><issue><style face="normal" font="default" size="100%">2 S</style></issue><notes><style face="normal" font="default" size="100%">Cited By :21Export Date: 21 February 2017</style></notes></record></records></xml>