@article {637,
	title = {Rhinovirus viremia in children with respiratory infections},
	journal = {Am J Respir Crit Care Med},
	volume = {172},
	number = {8},
	year = {2005},
	pages = {1037-40},
	type = {Journal Article},
	abstract = {{Viremia has been implicated in many viral infections; however, viremia due to rhinovirus (RV; rhinoviremia) has been considered not to occur in normal individuals.|To evaluate whether RV enters the bloodstream and identify the possible risk factors.|Nasopharyngeal washes (NPWs) of 221 children with respiratory infections were examined for the presence of RV by reverse transcription-polymerase chain reaction. Blood from 88 children, whose NPW was RV-positive, and 31 of RV-negative control subjects was subsequently examined for the presence of RV in the blood by semi-nested reverse transcription-polymerase chain reaction. Rhinoviremia was then correlated with clinical characteristics of the disease.|RV was detected in the blood of 10 out of 88 NPW RV-positive cases (11.4\%): 7 of 28 children with asthma exacerbations (25.0\%), 2 of 26 with common cold (7.7\%), 1 of 25 with bronchiolitis (4.0\%), and 0 of 9 with pneumonia (0\%). All NPW RV-negative cases were negative in the blood. The proportion of rhinoviremia in children with asthma exacerbation was significantly higher compared with children suffering from the other diseases (25 vs. 5\%},
	keywords = {Acute Disease Adolescent Asthma Bronchiolitis Case-Control Studies Child Child, Agar Gel Female Greece Hospitals, Pediatric Humans Infant Logistic Models Male Multivariate Analysis Nasal Lavage Fluid Pneumonia, Preschool Common Cold DNA, Viral Electrophoresis, Viral Reverse Transcriptase Polymerase Chain Reaction Rhinovirus Risk Factors Severity of Illness Index Viremia},
	issn = {1073-449X},
	doi = {10.1164/rccm.200502-315OC},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/15994468},
	author = {Xatzipsalti, M. and Kyrana, S. and Tsolia, M. and Psarras, S. and Bossios, A. and Laza-Stanca, V. and Johnston, S. L. and Papadopoulos, N. G.}
}
