@article {38976,
	title = {Adjunctive low-dose amisulpride in motor conversion disorder},
	journal = {Clin Neuropharmacol},
	volume = {32},
	number = {6},
	year = {2009},
	note = {doi: 10.1097/WNF.0b013e3181b20144.},
	month = {Nov-Dec},
	pages = {342-3},
	abstract = {Extant pharmacological options for motor conversion disorder include mainly antidepressants and benzodiazepines. We report on the case of a 42-year-old female patient with frequent daily episodes of almost complete paralysis for the last 6 months resistant to an escitalopram-lorazepam combination at adequate doses. By contrast, the adjunctive administration of low-dose amisulpride at 200 mg/d to the patient{\textquoteright}s regimen resulted in her substantial and durable improvement. We hypothesize that low-dose amisulpride, acting as a selective antagonist of D2 and D3 dopamine autoreceptors, might reverse the decreased activity of frontal and subcortical dopaminergic circuits presumably involved in motor control during hysterical paralysis.},
	keywords = {Adult, Amisulpride, Citalopram/therapeutic use, Conversion Disorder/*drug therapy/physiopathology, Dopamine Antagonists/*therapeutic use, Drug Combinations, Drug Therapy, Combination, Female, Humans, Lorazepam/therapeutic use, Motor Cortex/*drug effects/physiopathology, Paraplegia/drug therapy/psychology, Psychomotor Disorders/*drug therapy/physiopathology, Selective Serotonin Reuptake Inhibitors/therapeutic use, Sulpiride/*analogs \& derivatives/therapeutic use, Treatment Outcome},
	isbn = {0362-5664},
	author = {Oulis, P. and Kokras, N and Papadimitriou, G.N. and Masdrakis, V. G.}
}
