Pinotsis N, Zielinska K, Babuta M, Arolas JL, Kostan J, Khan MB, Schreiner C, Salmazo A, Ciccarelli L, Puchinger M, et al. Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc Natl Acad Sci U S A. 2020;117:22101-22112.