@article {187,
	title = {Invited commentary: lipoproteins and dementia - is it the apolipoprotein A-I?},
	journal = {Am J Epidemiol},
	volume = {165},
	year = {2007},
	month = {2007 May 1},
	pages = {993-7},
	abstract = {Because of the aging of the population, dementia has become a major public health problem. There has been growing evidence for a possible association between lipids and dementia. A large body of literature has demonstrated multiple hypothesized biologic links between lipids and neurodegenerative or other biologic pathways connected to dementing processes. However, the epidemiologic associations have been conflicting: dyslipidemia at middle age, but not in later life, seems to be associated with higher dementia risk in some but not all studies. Results from the Honolulu-Asia Aging Study reported by Saczynski et al. (Am J Epidemiol 2007;165:985-92) suggest that lipoprotein constituents, such as apolipoprotein A-I, a major component of the high density lipoprotein, may be more informative in enlightening the association between lipids and dementia. In this commentary, the epidemiology and biology of apolipoprotein A-I in relation to dementia is reviewed.},
	keywords = {Aging, Apolipoprotein A-I, Cholesterol, HDL, Dementia, Humans, Inflammation, Lipoproteins, Risk Factors},
	issn = {0002-9262},
	doi = {10.1093/aje/kwm033},
	author = {Scarmeas, Nikolaos}
}
