@article {217,
	title = {APOE-dependent PET patterns of brain activation in Alzheimer disease.},
	journal = {Neurology},
	volume = {63},
	year = {2004},
	month = {2004 Sep 14},
	pages = {913-5},
	abstract = {Using H2(15)O PET, the authors imaged 13 patients with Alzheimer disease (AD) while performing a serial nonverbal recognition memory task. Patterns of brain activation differed as a function of APOE genotype: epsilon4 carriers exhibited lower activation in the left lingual gyrus and higher activation in left cuneus, precuneus, parahippocampal, and right precentral gyrus. The APOE genotype seems to play a role in cerebral physiologic activity even after onset of clinical manifestations of AD.},
	keywords = {Age of Onset, Alleles, Alzheimer Disease, Apolipoprotein E4, Apolipoproteins E, Brain, Brain Mapping, Female, Genotype, Humans, Male, Memory Disorders, Mental Recall, Middle Aged, Neuropsychological Tests, Pattern Recognition, Visual, Positron-Emission Tomography},
	issn = {1526-632X},
	author = {Scarmeas, N. and Anderson, K E and Hilton, J and Park, A and Habeck, C and Flynn, J and Tycko, B and Stern, Y}
}
