@article {43616,
	title = {Trimerisation of carbon suboxide at a di-titanium centre to form a pyrone ring system},
	journal = {Chemical Science},
	volume = {9},
	year = {2018},
	month = {2018},
	pages = {5008 - 5014},
	publisher = {Royal Society of Chemistry},
	abstract = {The reaction of the syn-bimetallic bis(pentalene)dititanium complex Ti2(μ:η5,η5-Pn{\textdagger})2 (Pn{\textdagger} = C8H4(1,4-SiiPr3)2) 1 with carbon suboxide (OCCCO, C3O2) results in trimerisation of the latter and formation of the structurally characterised complex [{Ti2(μ:η5,η5-Pn{\textdagger})2}{μ-C9O6}]. The trimeric bridging C9O6 unit in the latter contains a 4-pyrone core, a key feature of both the hexamer and octamer of carbon suboxide which are formed in the body from trace amounts of C3O2 and are, for example, potent inhibitors of Na+/K+-ATP-ase. The mechanism of this reaction has been studied in detail by DFT computational studies, which also suggest that the reaction proceeds via the initial formation of a mono-adduct of 1 with C3O2. Indeed, the carefully controlled reaction of 1 with C3O2 affords [Ti2(μ:η5,η5-Pn{\textdagger})2 (η2-C3O2)], as the first structurally authenticated complex of carbon suboxide.},
	author = {Tsoureas, Nikolaos and Green, Jennifer C. and Cloke, F. Geoffrey N. and Puschmann, Horst and Roe, S. Mark and Tizzard, Graham}
}
