<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cao, Shu-Qin</style></author><author><style face="normal" font="default" size="100%">Wang, He-Ling</style></author><author><style face="normal" font="default" size="100%">Palikaras, Konstantinos</style></author><author><style face="normal" font="default" size="100%">Tavernarakis, Nektarios</style></author><author><style face="normal" font="default" size="100%">Fang, Evandro Fei</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemotaxis assay for evaluation of memory-like behavior in wild-type and Alzheimer's-disease-like C. elegans models</style></title><secondary-title><style face="normal" font="default" size="100%">STAR protocols</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Molecular Biology</style></keyword><keyword><style  face="normal" font="default" size="100%">neuroscience</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2023</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://dx.doi.org/10.1016/j.xpro.2023.102250https://www.ncbi.nlm.nih.gov/pubmed/37104093https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154957</style></url></web-urls></urls><publisher><style face="normal" font="default" size="100%">Elsevier BV</style></publisher><volume><style face="normal" font="default" size="100%">4</style></volume><pages><style face="normal" font="default" size="100%">102250</style></pages><isbn><style face="normal" font="default" size="100%">2666-1667</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Here, we present an olfactory-dependent chemotaxis assay for evaluating changes in memory-like behavior in both wild-type and Alzheimer's-disease-like C. elegans models. We describe steps for synchronizing and preparing C. elegans populations and for performing isoamyl alcohol conditioning during starvation and chemotaxis assaying. We then detail counting and quantification procedures. This protocol is applicable to mechanistic exploration and drug screening in neurodegenerative diseases and brain aging.</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue></record></records></xml>