@article {44016,
	title = {Open reconstructions for symptomatic atherosclerotic lesions of the supra-aortic vessels: thirty years results from two university hospitals.},
	journal = {Ann Vasc Surg},
	volume = {29},
	year = {2015},
	month = {2015 Apr},
	pages = {404-10},
	abstract = {BACKGROUND: Atherosclerotic lesions at the origin of common carotid, subclavian, and innominate arteries are causes for brain and hand ischemic symptoms. Surgical reconstructions of symptomatic cases remain the golden standard treatment, although the endovascular approach has been promising as well. In this retrospective study, long-term results of open reconstructions from 2 University Hospitals are presented.

METHODS: Through a 30-year period, prospective data of 107 patients, suffering from symptomatic atherosclerotic supra-aortic artery disease, were retrospectively reviewed and included in this study. Demographic data, arterial risk factors, presenting symptoms and signs, diagnostic evaluation, operative treatment and complications, resolution of symptoms, redo surgery, and overall mortality were analyzed.

RESULTS: Eighty-one patients were operated on for subclavian, 14 for innominate, and 12 for common carotid severe lesions, through an extra-thoracic reconstruction (91 patients) or a transthoracic one (16 patients). Perioperative mortality was null although morbidity was 16.8\%, and primary perioperative patency was 97.2\% (secondary patency 100\%). The cumulative primary patency was 95.3\%, 90.7\%, and 86.0\% at 5, 10, and 15 years, respectively. The mean time of patency was 214.6 months (95\% confidence interval = 198.5-230.6), with no difference between transthoracic and extrathoracic reconstructions (P = 0.278).

CONCLUSIONS: Open reconstructions remain a therapeutic strategy with a considerably low perioperative morbidity/mortality offering excellent long-term results regarding patency of the reconstructions and clinical resolution of the symptoms. However, in the modern era of the endovascular techniques, we need more studies for establishing anatomic and clinical criteria regarding patient selection for endovascular angioplasty/stenting or open repair.},
	keywords = {Adult, Aged, Atherosclerosis, Brachiocephalic Trunk, Carotid Artery Diseases, Carotid Artery, Common, Female, Germany, Greece, Hospitals, University, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Plastic Surgery Procedures, Retrospective Studies, Risk Factors, Subclavian Artery, Time Factors, Treatment Outcome, Vascular Patency},
	issn = {1615-5947},
	doi = {10.1016/j.avsg.2014.09.027},
	author = {Sigala, Fragiska and Galyfos, George and Coutelle, Alexander G and Antonakis, Pantelis and Sigalas, Panagiotis and Bastounis, Elias and Hepp, Wolfgang and Filis, Konstantinos}
}
