@article {587,
	title = {Disparity in circulating adiponectin multimers between term and preterm infants.},
	journal = {J Perinat Med},
	volume = {37},
	year = {2009},
	month = {2009},
	pages = {683-8},
	abstract = {AIMS: To study circulating levels and distribution of adiponectin multimers [low molecular weight (LMW)-, medium molecular weight (MMW)- and high molecular weight (HMW)-adiponectin] in preterm and full-term infants. METHODS: Total serum adiponectin and its multimers were measured in 40 healthy infants at the age of one month and associations with anthropometric parameters [body weight and length, body mass index (BMI)], weight gain and metabolic indices (glucose, insulin) were examined. Twenty of the infants were born preterm (gestational age 33.2+/-1.6 weeks). RESULTS: LMW-adiponectin level and its fractional ratio to total adiponectin were significantly higher in full-term than in preterm infants (P<0.001 and P<0.01, respectively), whereas, MMW-adiponectin level and its ratio were significantly lower (P=0.03 and P=0.01, respectively). HMW-adiponectin did not differ significantly between full-term and preterm infants and accounted for almost 60\% of total adiponectin levels in both groups. HMW-adiponectin, but not MMW adiponectin or LMW adiponectin, correlated significantly with anthropometric measurements, similarly to total adiponectin; in addition, HMW adiponectin correlated significantly with weight gain. CONCLUSIONS: HMW adiponectin is the most prevalent form in infants. Circulating levels and distribution of MMW- and LMW-adiponectin differ between full-term and preterm infants, but the role of these adiponectin multimers needs to be studied further.},
	keywords = {Adiponectin, Birth Weight, Body Mass Index, Case-Control Studies, Female, Gestational Age, Humans, Infant, Male, Molecular Weight, Newborn, Pregnancy, Premature, Protein Structure, Quaternary, Weight Gain},
	issn = {1619-3997},
	doi = {10.1515/JPM.2009.116},
	author = {Tania Siahanidou and Margeli, Alexandra and Garatzioti, Maria and Davradou, Maria and Apostolakou, Filia and Papassotiriou, Ioannis and Mandyla, Helen}
}
