Saccadic eye movement tasks have been widely used as a probe for measuring cognitive functions in healthy humans as well as in patients with neurological and psychiatric disorders. Circadian variation has been shown to affect multiple aspects of cognitive function especially executive function related to prefrontal cortex. The effects of diurnal variation in saccadic task performance and the dissociation of these effects from repetition or practice effects has not been adequately addressed. In the current study thirty healthy adults performed several saccadic eye movement tasks including visually guided saccades, antisaccades and countermanding saccades in three consecutive sessions. Participants were divided into three groups, with a different starting time of the sequence of the three sessions across groups (morning or afternoon or evening) to examine the effect of diurnal variation (time of day that the tasks were performed) separated from the effect of session repetition (practice effect). The results showed no effect of diurnal variation for all indexes of saccadic eye movement performance including accuracy (antisaccade and countermanding saccade tasks) speed (mean latency in all tasks) and stability (intra-subject standard deviation of latency in all tasks). In contrast, saccadic task repetition significantly improved accuracy, speed and stability of performance indicating the presence of practice effects in these tasks. Finally, linear mixed model analysis confirmed no interaction between diurnal variation and practice effects for all indexes of saccadic eye movement performance. In conclusion our study provides confirmation that saccadic task performance is not affected by diurnal variation related to circadian rhythms. In contrast, short term repetition of these tasks results in significant practice effects.

Processing of sensory stimuli generated by our own actions differs from that of externally generated stimuli. However, most evidence regarding this phenomenon concerns the processing of unisensory stimuli. A few studies have explored the effect of self-generated actions on multisensory stimuli and how it affects the integration of these stimuli. Most of them used abstract stimuli (e.g., flashes, beeps) rather than more natural ones such as sensations that are commonly correlated with actions that we perform in our everyday lives such as speech. In the current study, we explored the effect of self-generated action on the process of multisensory integration (MSI) during speech. We used a novel paradigm where participants were either listening to the echo of their own speech, while watching a video of themselves producing the same speech (“talk”, active condition), or they listened to their previously recorded speech and watched the prerecorded video of themselves producing the same speech (“listen”, passive condition). In both conditions, different stimulus onset asynchronies were introduced between the auditory and visual streams and participants were asked to perform simultaneity judgments. Using these judgments, we determined temporal binding windows (TBW) of integration for each participant and condition. We found that the TBW was significantly smaller in the active as compared to the passive condition indicating more accurate MSI. These results support the conclusion that sensory perception is modulated by self-generated action at the multisensory in addition to the unisensory level.