<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Magrioti, V.</style></author><author><style face="normal" font="default" size="100%">Constantinou-Kokotou, V.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Synthesis of (S)-α-amino oleic acid</style></title><secondary-title><style face="normal" font="default" size="100%">Lipids</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2002</style></year></dates><number><style face="normal" font="default" size="100%">2</style></number><volume><style face="normal" font="default" size="100%">37</style></volume><pages><style face="normal" font="default" size="100%">223-228</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;span&gt;An efficient synthesis of (&lt;/span&gt;&lt;em class=&quot;EmphasisTypeItalic &quot;&gt;S&lt;/em&gt;&lt;span&gt;)-α-amino oleic acid was developed. The fully protected FA derivative was obtained in four steps starting from methyl (2&lt;/span&gt;&lt;em class=&quot;EmphasisTypeItalic &quot;&gt;S&lt;/em&gt;&lt;span&gt;)-2-[bis(&lt;/span&gt;&lt;em class=&quot;EmphasisTypeItalic &quot;&gt;tert&lt;/em&gt;&lt;span&gt;-butoxycar-bonyl)amino]-5-oxopentanoate. These steps are (i) olefination of the starting aldehyde with the appropriate phosphonate anion, (ii) hydrogenation of the double bonds, (iii) controlled reduction of ω-ethyl ester to an aldehyde in the presence of α-methyl ester, and (iv) a Wittig reaction of the latter aldehyde with the suitable ylide. Free α-amino oleic acid was prepared after deprotection of the amino group followed by saponification in a total yield of 24%.&amp;nbsp;&lt;/span&gt;&lt;em class=&quot;EmphasisTypeItalic &quot;&gt;N-tert&lt;/em&gt;&lt;span&gt;-Butoxycarbonyl-protected amino oleic acid and the corresponding amino alcohol were prepared in high yield. The structures of the products have been established by various spectroscopic techniques.&lt;/span&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Article</style></work-type><notes><style face="normal" font="default" size="100%">Cited By :10Export Date: 18 January 2017</style></notes><remote-database-name><style face="normal" font="default" size="100%">Scopus</style></remote-database-name></record></records></xml>