@article {17411,
	title = {Human herpesvirus 8 (HHV-8) infection in healthy urban employees from Greece: seroprevalence and associated factors},
	journal = {J Med VirolJ Med VirolJ Med Virol},
	volume = {79},
	number = {5},
	year = {2007},
	note = {Zavitsanou, AssiminaSypsa, VanaPetrodaskalaki, MariaKalapothaki, VictoriaWhitby, DeniseHatzakis, AngelosengN01-CO-12400/CO/NCI NIH HHS/Research Support, N.I.H., Extramural2007/03/28 09:00J Med Virol. 2007 May;79(5):591-6. doi: 10.1002/jmv.20812.},
	month = {May},
	pages = {591-6},
	abstract = {A cross-sectional study was carried out in healthy company employees from Greece with the aim of assessing the prevalence of human herpesvirus 8 (HHV-8) and identifying risk factors for this herpesviral infection. Serum samples obtained from 955 subjects were tested for antibodies to HHV-8 by the K8.1 enzyme-linked immunosorbent assay (ELISA). Associations between HHV-8 serostatus and potential risk factors were examined using t-test, chi square test, and multivariate logistic regression analysis. HHV-8 prevalence was 7.6\% (95\% confidence interval (CI): 6.0\%, 9.5\%) and it increased with age from 6.5\% among <30 years old to 13.8\% among > or =50 years old subjects (P = 0.006). HHV-8 seropositivity was independently associated with endoscopic examination (odds ratio (OR): 2.01; 95\% CI: 1.09, 3.70; P = 0.026), HBsAg positivity (OR: 5.16; 95\% CI: 2.02, 13.20; P = 0.001) and age (OR > or =50 years old vs. <50 years old: 2.09; 95\% CI: 1.23, 3.52; P = 0.006). No statistically significant associations between HHV-8 positive status and gender, occupational status, surgery, transfusion, tattoos/body piercing, multiple sex partners, weakness/fatigue, HCV status were observed. HHV-8 is prevalent in Greece. The strong association between HBV infection and HHV-8 positive status supports the hypothesis of an association between these two viral infections. The association between HHV-8 seropositivity and endoscopic examination requires further investigation.},
	keywords = {Adolescent, Adult, Age Factors, Aged, Antibodies, Viral/*blood, Carrier State/epidemiology, Cross-Sectional Studies, Enzyme-Linked Immunosorbent Assay, Female, Greece/epidemiology, Herpesviridae Infections/*blood/*epidemiology, Herpesvirus 8, Human/*immunology, Humans, Male, Middle Aged, Occupational Health, Prevalence, Risk Factors, Seroepidemiologic Studies, urban population},
	isbn = {0146-6615 (Print)0146-6615 (Linking)},
	author = {Zavitsanou, A and Sypsa, V and Petrodaskalaki, M. and Kalapothaki, V and Whitby, D. and Hatzakis, A}
}
