@article {17416,
	title = {Human herpesvirus 8 infection in hemodialysis patients},
	journal = {Am J Kidney DisAm J Kidney DisAm J Kidney Dis},
	volume = {47},
	number = {1},
	year = {2006},
	note = {Zavitsanou, AssiminaSypsa, VanaPetrodaskalaki, MariaPsichogiou, MinaKatsoulidou, AntigoniBoletis, JohnHadjiconstantinou, ValsamakisKaralis, DimitrisKalapothaki, VictoriaHatzakis, AngelosengCase Reports2005/12/27 09:00Am J Kidney Dis. 2006 Jan;47(1):167-70. doi: 10.1053/j.ajkd.2005.09.019.},
	month = {Jan},
	pages = {167-70},
	abstract = {BACKGROUND: The aim of the present study was to evaluate human herpesvirus 8 (HHV-8) seroprevalence in Greek hemodialysis patients. Patterns of change in HHV-8 serostatus (seroconversions and seroreversions) over time were also evaluated. METHODS: Serum samples obtained from a cohort of 485 Greek hemodialysis patients were tested for antibodies to HHV-8 by whole virus lysate enzyme-linked immunosorbent assay, and reactive samples were confirmed by means of the orf-73 enzyme-linked immunosorbent assay. HHV-8 seroprevalence at study entry and the incidence of seroreversions and seroconversions per 100 person-years were estimated. RESULTS: The prevalence of HHV-8 antibodies in Greek hemodialysis patients at enrollment was 7.2\%. No univariate associations were established between HHV-8 serostatus and patients{\textquoteright} characteristics. Incidences of seroreversions and seroconversions were 16.4/100 person-years (95\% confidence interval, 7.1 to 32.3) and 0.28/100 person-years (95\% confidence interval, 0.03 to 1.02), respectively. Patients 50 years and younger had an increased probability for seroreversion to HHV-8 antibodies than patients older than 50 years (log-rank test, P = 0.018). CONCLUSION: We observed a fair number of seroreversions and a low incidence of seroconversion to HHV-8 infection in hemodialysis patients in Greece. Our data provide indirect evidence that HHV-8 transmission in the hemodialysis setting is uncommon.},
	keywords = {*Renal Dialysis/adverse effects, Adult, Aged, Antibodies, Viral/biosynthesis/*blood, Cohort Studies, Comorbidity, Disease Transmission, Infectious, Female, Follow-Up Studies, Greece/epidemiology, Hepatitis, Viral, Human/epidemiology, Hepatomegaly/epidemiology, Herpesviridae Infections/diagnosis/*epidemiology/transmission/virology, Herpesvirus 8, Human/*immunology, Humans, Immunoglobulin G/biosynthesis/blood, Incidence, Kidney Failure, Chronic/blood/*epidemiology/therapy/virology, Kidney Transplantation, Male, Middle Aged, Multicenter Studies as Topic, Prevalence, Splenomegaly/epidemiology, Transfusion Reaction},
	isbn = {1523-6838 (Electronic)0272-6386 (Linking)},
	author = {Zavitsanou, A and Sypsa, V and Petrodaskalaki, M. and Psichogiou, M and Katsoulidou, A and Boletis, J. and Hadjiconstantinou, V. and Karalis, D. and Kalapothaki, V and Hatzakis, A}
}
