@article {17428,
	title = {Comparison of three current viral load assays for the quantitation of human immunodeficiency virus type 1 RNA in plasma},
	journal = {J Virol MethodsJ Virol MethodsJ Virol Methods},
	volume = {121},
	number = {1},
	year = {2004},
	note = {Katsoulidou, AntigoniPapachristou, EleniPetrodaskalaki, MariaSypsa, VanaAnastassopoulou, Cleo GGargalianos, PanagiotisKarafoulidou, AnastasiaLazanas, MariosKordossis, TheodorosAndoniadou, AnastasiaHatzakis, AngelosengComparative StudyNetherlands2004/09/08 05:00J Virol Methods. 2004 Oct;121(1):93-9. doi: 10.1016/j.jviromet.2004.06.007.},
	month = {Oct},
	pages = {93-9},
	abstract = {The LCx HIV RNA quantitative assay (Abbott Laboratories, Delkenheim, Germany) was compared with the Versant HIV-1 RNA 3.0 (bDNA) assay (Bayer, Tarrytown, NY) and the COBAS Amplicor HIV-1 Monitor v1.5 test (Roche Diagnostics, Branchburg, NJ), using plasma samples of various viral load levels from HIV-1-infected patients. Considering the lower limit of the linear range of 50 copies/ml of both assays, the detection range of the LCx was 127/151 (84.1\%) versus the 131/151 (86.8\%) of the bDNA 3.0 assay, while overall agreement between the two assays was 93.4\% (141/151). LCx and bDNA 3.0 results were found to be strongly correlated (r = 0.96). The fitted regression line was described by the equation log10(LCx copies/ml) = 0.05 + 1.06 x log10(bDNA 3.0 copies/ml) with 95\% CI for the estimated slope and intercept at 1.01, 1.12 and -0.16, 0.26, respectively. Similarly, the detection range of the LCx was 115/148 (77.7\%) versus the 128/148 (86.5\%) of the Monitor v1.5 test. A 91.2\% concordance (135/148) was observed between these two assays at a cut-off of 50 copies/ml. LCx and Monitor v1.5 results were highly correlated (r = 0.96). The fitted regression line was described by the equation log10(LCx copies/ml) = 0.06 + 1.03 x log(10)(Monitor v1.5 copies/ml) with 95\% CI for the estimated slope and intercept at 0.97, 1.09 and -0.16, 0.28, respectively.},
	keywords = {*Viral Load, HIV-1/*isolation \& purification, Humans, Molecular Diagnostic Techniques/methods, Reagent Kits, Diagnostic, Regression Analysis, RNA, Viral/*blood, Sensitivity and Specificity},
	isbn = {0166-0934 (Print)0166-0934 (Linking)},
	author = {Katsoulidou, A and Papachristou, E. and Petrodaskalaki, M. and Sypsa, V and Anastassopoulou, C. G. and Gargalianos, P and Karafoulidou, A. and Lazanas, M and Kordossis, T. and Andoniadou, A. and Hatzakis, A}
}
