<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kostaki, E. G.</style></author><author><style face="normal" font="default" size="100%">Nikolopoulos, G K</style></author><author><style face="normal" font="default" size="100%">Pavlitina, E.</style></author><author><style face="normal" font="default" size="100%">Williams, L.</style></author><author><style face="normal" font="default" size="100%">Magiorkinis, G</style></author><author><style face="normal" font="default" size="100%">Schneider, J.</style></author><author><style face="normal" font="default" size="100%">Skaathun, B.</style></author><author><style face="normal" font="default" size="100%">Morgan, E.</style></author><author><style face="normal" font="default" size="100%">Psichogiou, M</style></author><author><style face="normal" font="default" size="100%">Daikos, G L</style></author><author><style face="normal" font="default" size="100%">Sypsa, V</style></author><author><style face="normal" font="default" size="100%">Smyrnov, P.</style></author><author><style face="normal" font="default" size="100%">Korobchuk, A.</style></author><author><style face="normal" font="default" size="100%">Malliori, M.</style></author><author><style face="normal" font="default" size="100%">Hatzakis, A</style></author><author><style face="normal" font="default" size="100%">Friedman, S. R.</style></author><author><style face="normal" font="default" size="100%">Paraskevis, D</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Molecular Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals in a Network-Based Intervention (Transmission Reduction Intervention Project): Phylogenetics Identify HIV-1-Infected Individuals With Social Links</style></title><secondary-title><style face="normal" font="default" size="100%">J Infect Dis</style></secondary-title><alt-title><style face="normal" font="default" size="100%">The Journal of infectious diseases</style></alt-title><short-title><style face="normal" font="default" size="100%">J Infect DisJ Infect Dis</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">*Disease Transmission, Infectious</style></keyword><keyword><style  face="normal" font="default" size="100%">*Genotype</style></keyword><keyword><style  face="normal" font="default" size="100%">*Social Networking</style></keyword><keyword><style  face="normal" font="default" size="100%">Adolescent</style></keyword><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Aged, 80 and over</style></keyword><keyword><style  face="normal" font="default" size="100%">Cluster analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Drug Users</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Genotyping Techniques</style></keyword><keyword><style  face="normal" font="default" size="100%">HIV Infections/*epidemiology/*transmission</style></keyword><keyword><style  face="normal" font="default" size="100%">HIV-1/*classification/*genetics/isolation &amp; purification</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">molecular epidemiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Phylogeny</style></keyword><keyword><style  face="normal" font="default" size="100%">Sequence Analysis, DNA</style></keyword><keyword><style  face="normal" font="default" size="100%">Substance Abuse, Intravenous/complications</style></keyword><keyword><style  face="normal" font="default" size="100%">Surveys and Questionnaires</style></keyword><keyword><style  face="normal" font="default" size="100%">Young Adult</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jul 24</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">5</style></number><volume><style face="normal" font="default" size="100%">218</style></volume><pages><style face="normal" font="default" size="100%">707-715</style></pages><isbn><style face="normal" font="default" size="100%">1537-6613 (Electronic)0022-1899 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Background: The Transmission Reduction Intervention Project (TRIP) is a network-based intervention that aims at decreasing human immunodeficiency virus type 1 (HIV-1) spread. We herein explore associations between transmission links as estimated by phylogenetic analyses, and social network-based ties among persons who inject drugs (PWID) recruited in TRIP. Methods: Phylogenetic trees were inferred from HIV-1 sequences of TRIP participants. Highly supported phylogenetic clusters (transmission clusters) were those fulfilling 3 different phylogenetic confidence criteria. Social network-based ties (injecting or sexual partners, same venue engagement) were determined based on personal interviews, recruitment links, and field observation. Results: TRIP recruited 356 individuals (90.2% PWID) including HIV-negative controls; recently HIV-infected seeds; long-term HIV-infected seeds; and their social network members. Of the 150 HIV-infected participants, 118 (78.7%) were phylogenetically analyzed. Phylogenetic analyses suggested the existence of 13 transmission clusters with 32 sequences. Seven of these clusters included 14 individuals (14/32 [43.8%]) who also had social ties with at least 1 member of their cluster. This proportion was significantly higher than what was expected by chance. Conclusions: Molecular methods can identify HIV-infected people socially linked with another person in about half of the phylogenetic clusters. This could help public health efforts to locate individuals in networks with high transmission rates.</style></abstract><accession-num><style face="normal" font="default" size="100%">29697829</style></accession-num><notes><style face="normal" font="default" size="100%">Kostaki, Evangelia-GeorgiaNikolopoulos, Georgios KPavlitina, EiriniWilliams, LeslieMagiorkinis, GkikasSchneider, JohnSkaathun, BrittMorgan, EthanPsichogiou, MinaDaikos, Georgios LSypsa, VanaSmyrnov, PavloKorobchuk, AniaMalliori, MeniHatzakis, AngelosFriedman, Samuel RParaskevis, DimitriosengP30 DA011041/DA/NIDA NIH HHS/T32 AI007384/AI/NIAID NIH HHS/DP1 DA034989/DA/NIDA NIH HHS/Research Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't2018/04/27 06:00J Infect Dis. 2018 Jul 24;218(5):707-715. doi: 10.1093/infdis/jiy239.</style></notes><custom2><style face="normal" font="default" size="100%">6057507</style></custom2><auth-address><style face="normal" font="default" size="100%">Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Greece.Medical School, University of Cyprus, Nicosia.Transmission Reduction Intervention Project, Athens, Greece.National Development and Research Institutes, New York, New York.Departments of Medicine and Public Health Sciences, University of Chicago Medical Center, Center for AIDS Elimination, Illinois.Laikon General Hospital, First Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Greece.Alliance for Public Health, Kyiv, Ukraine.Medical School, National and Kapodistrian University of Athens, Greece.</style></auth-address></record></records></xml>