<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Zavitsanou, A</style></author><author><style face="normal" font="default" size="100%">Malliori, M.</style></author><author><style face="normal" font="default" size="100%">Sypsa, V</style></author><author><style face="normal" font="default" size="100%">Petrodaskalaki, M.</style></author><author><style face="normal" font="default" size="100%">Psichogiou, M</style></author><author><style face="normal" font="default" size="100%">Rokka, C</style></author><author><style face="normal" font="default" size="100%">Giannopoulos, A</style></author><author><style face="normal" font="default" size="100%">Kalapothaki, V</style></author><author><style face="normal" font="default" size="100%">Whitby, D.</style></author><author><style face="normal" font="default" size="100%">Hatzakis, A</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Seroepidemiology of human herpesvirus 8 (HHV-8) infection in injecting drug users</style></title><secondary-title><style face="normal" font="default" size="100%">Epidemiol InfectEpidemiol InfectEpidemiol Infect</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Epidemiology and infection</style></alt-title><short-title><style face="normal" font="default" size="100%">Epidemiology and infectionEpidemiology and infection</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">*Seroepidemiologic Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">*Substance Abuse, Intravenous</style></keyword><keyword><style  face="normal" font="default" size="100%">Adolescent</style></keyword><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Antibodies, Viral/blood</style></keyword><keyword><style  face="normal" font="default" size="100%">Cross-Sectional Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Greece/epidemiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Herpesviridae Infections/*blood/*epidemiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Herpesvirus 8, Human/*isolation &amp; purification</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Young Adult</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2010</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Mar</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">3</style></number><volume><style face="normal" font="default" size="100%">138</style></volume><pages><style face="normal" font="default" size="100%">403-8</style></pages><isbn><style face="normal" font="default" size="100%">1469-4409 (Electronic)0950-2688 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">A cross-sectional study was carried out in injecting drug users (IDUs) from Greece to assess the seroprevalence of human herpesvirus 8 (HHV-8) and to identify potentially associated risk factors. A total of 288 IDUs were tested for K8.1 antibodies to HHV-8 lytic antigen. Associations between HHV-8 serostatus and potential risk factors were examined using univariate and multivariate logistic regression analysis. Seroprevalence of HHV-8 was 24.3% (95% CI 19.5-29.7), increasing with age from 19.4% in those aged &lt;30 years to 52.9% in those aged 40 years (P for trend=0.003). No statistically significant associations between HHV-8-positive status and gender, educational level, age at first drug injection, needle sharing, number of imprisonments, complications from drug overdose, HIV and HCV were observed. In the multivariate logistic regression analysis, older age (40 vs. &lt;40 years, OR 3.30, 95% CI 1.14-9.56) and report of septicaemia/abscess (yes vs. no, OR 1.80, 95% CI 1.01-3.18) were each independently associated with higher HHV-8 seroprevalence. HHV-8 is highly prevalent in the IDU population in Greece. The independent association between HHV-8 and reported abscess or septicaemia supports the hypothesis that poor hygiene conditions in the setting of drug injection may contribute to HHV-8 transmission.</style></abstract><accession-num><style face="normal" font="default" size="100%">19698211</style></accession-num><notes><style face="normal" font="default" size="100%">Zavitsanou, AMalliori, MSypsa, VPetrodaskalaki, MPsichogiou, MRokka, CGiannopoulos, AKalapothaki, VWhitby, DHatzakis, AengResearch Support, Non-U.S. Gov'tEngland2009/08/25 09:00Epidemiol Infect. 2010 Mar;138(3):403-8. doi: 10.1017/S0950268809990628. Epub 2009 Aug 24.</style></notes><auth-address><style face="normal" font="default" size="100%">Department of Hygiene, Epidemiology and Medical Statistics, Athens University Medical School, Athens, Greece.</style></auth-address></record></records></xml>