<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Spyridopoulou, K.</style></author><author><style face="normal" font="default" size="100%">Psichogiou, M</style></author><author><style face="normal" font="default" size="100%">Sypsa, V</style></author><author><style face="normal" font="default" size="100%">Miriagou, V.</style></author><author><style face="normal" font="default" size="100%">Karapanou, A.</style></author><author><style face="normal" font="default" size="100%">Hadjihannas, L.</style></author><author><style face="normal" font="default" size="100%">Tzouvelekis, L.</style></author><author><style face="normal" font="default" size="100%">Daikos, G L</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Containing Carbapenemase-producing Klebsiella pneumoniae in an endemic setting</style></title><secondary-title><style face="normal" font="default" size="100%">Antimicrob Resist Infect Control</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Antimicrobial resistance and infection control</style></alt-title><short-title><style face="normal" font="default" size="100%">Antimicrobial resistance and infection controlAntimicrobial resistance and infection control</style></short-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jul 6</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">102</style></pages><isbn><style face="normal" font="default" size="100%">2047-2994</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">BACKGROUND: Carbapenemase-producing K. pneumoniae (CP-Kp) has been established as important nosocomial pathogen in most tertiary care hospitals in Greece. The aim of the present study was to examine the impact of an enhanced infection control program on the containment of CP-Kp in a haematology unit where the incidence of CP-Kp infections was high. METHODS: The study was conducted from June 2011 to December 2014 in a haematology unit of a tertiary-care 500-bed hospital located in Athens, Greece. A bundled intervention (active surveillance cultures, separation of carriers from non-carriers, assignment of dedicated nursing staff, contact precautions, environmental cleaning, and promotion of hand hygiene) was tested whether would reduce colonization and infection caused by CP-Kp. RESULTS: A total of 2507 rectal swabs were obtained; 1199 upon admission from June 2011 to June 2013 and 1307 during hospitalization from June 2011 to December 2012. During intervention the admission prevalence of CP-Kp colonization (p &amp;lt; 0.001 for linear trend), the hospitalization prevalence (p = 0.001 for linear trend) and the incidence rate of CP-Kp colonization (p = 0.072 for linear trend) were declining. Application of segmented linear regression revealed that both the change in the level of CP-Kp BSI incidence rates (p = 0.001) as well as the difference between pre- and post-intervention slopes were statistically significant (p &amp;lt; 0.001). CONCLUSIONS: A bundled intervention including active surveillance cultures on admission can attain maximum containment of CP-Kp colonization and infection in endemic acute healthcare settings.</style></abstract><accession-num><style face="normal" font="default" size="100%">32631456</style></accession-num><notes><style face="normal" font="default" size="100%">2047-2994Spyridopoulou, KalliopiPsichogiou, MinaSypsa, VanaMiriagou, ViviKarapanou, AmaliaHadjihannas, LinosTzouvelekis, LeonidasDaikos, George LJournal ArticleEnglandAntimicrob Resist Infect Control. 2020 Jul 6;9(1):102. doi: 10.1186/s13756-020-00766-x.</style></notes><auth-address><style face="normal" font="default" size="100%">First Department of Medicine, Medical School, &quot;Laiko&quot; General Hospital, National and Kapodistrian University of Athens, 75, 11527, Athens, Greece.Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.Department of Microbiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.First Department of Medicine, Medical School, &quot;Laiko&quot; General Hospital, National and Kapodistrian University of Athens, 75, 11527, Athens, Greece. gdaikos@med.uoa.gr.</style></auth-address><remote-database-provider><style face="normal" font="default" size="100%">Nlm</style></remote-database-provider></record></records></xml>