He is a member of the Faculty of Theology of the National and Kapodistrian University of Athens (NKUA) since 2010. Having graduated from the same Faculty at 1993, he was granted the postgraduate degree of the University of Durham at 1997 (UK). A year later (1998) he received another postgraduate degree from the Faculty of Theology (NKUA). In the year 2002 he was nominated a Theology Doctor of the NKUA. He served as a teacher in Public (2007-2010) and Private (1999-2004) Schools of the Greek Secondary Education. He served as a Special Advisor to the GeneralSecretariat of Information (2004-2007). He also was member of the Greek Government as General Secretary of Mass Media (2012-2014).

His major academic interest and research lies within the area of General Church History. He has more than 40 scientific publications, with academic activity in three Universities (National and Kapodistrian University of Athens, Aristotle University of Thessaloniki, Open University of Cyprus) and he lectures in several Postgraduate Programs. Prof. Panagiotopoulos has extensive experience in Greek and European Programmes and Projects. He is in partnerships with nine (9) universities out of Greece and he has participated in more than a hundred international conferences. He has organized more than thirty (30) international conferences, he has taken place in the organization of three (3) Postgraduate Programs in Greece, and he is specialist in the organization of the academic curriculum of Short Courses (since 1995). He has also organized five (5) research expeditions and more than twenty (20) educational trips in Mount Athos.