Vassilios Myrianthopoulos studied pharmacy in NKUA, Greece. He received his PhD in 2010 from the same institute, working on rational design of small-molecule inhibitors of disease-relevant kinases with emphasis on molecules related to natural products. A part of his thesis was done at the Structural Genomics Consortium, University of Oxford, in the group of Professor Stefan Knapp. Among others, he has contributed to the development of two chemical probes, 6BIO and (R)-CR8, selectively targeting kinases GSK3β and CK1, respectively. From 2010 to 2018 he worked as a postdoctoral research fellow and a teaching associate in the Pharmaceutical Chemistry laboratory, University of Athens. His current research interests are focused on the combination of theoretical calculations and biophysical methodologies such as X-ray crystallography and fluorimetry for efficient hit identification and lead optimization, with special emphasis on the thermodynamic role of solvent in the drug-target interaction events. He has an on-going collaboration with research institutes including the Structural Genomics Consortium of Oxford and Goethe Universität of Frankfurt toward the discovery and optimization of small molecules as potent and selective inhibitors of proteins involved in signaling pathways and cellular senescence including protein kinases, epigenetic modules and metabolic enzymes. In 2019 he was appointed as assistant Professor in the Pharmacy department of NKUA.
Vassilios Myrianthopoulos studied pharmacy in NKUA, Greece. He received his PhD in 2010 from the same institute, working on rational design of small-molecule inhibitors of disease-relevant kinases with emphasis on molecules related to natural products. A part of his thesis was done at the Structural Genomics Consortium, University of Oxford, in the group of Professor Stefan Knapp. Among others, he has contributed to the development of two chemical probes, 6BIO and (R)-CR8, selectively targeting kinases GSK3β and CK1, respectively. From 2010 to 2018 he worked as a postdoctoral research fellow and a teaching associate in the Pharmaceutical Chemistry laboratory, University of Athens. His current research interests are focused on the combination of theoretical calculations and biophysical methodologies such as X-ray crystallography and fluorimetry for efficient hit identification and lead optimization, with special emphasis on the thermodynamic role of solvent in the drug-target interaction events. He has an on-going collaboration with research institutes including the Structural Genomics Consortium of Oxford and Goethe Universität of Frankfurt toward the discovery and optimization of small molecules as potent and selective inhibitors of proteins involved in signaling pathways and cellular senescence including protein kinases, epigenetic modules and metabolic enzymes. In 2019 he was appointed as assistant Professor in the Pharmacy department of NKUA.