Vassilios studied pharmacy in the University of Athens, Greece. He received his PhD in 2010 from the same institute, working on rational design of small-molecule inhibitors of disease-relevant kinases like GSK3β and the DYRKs, with emphasis on molecules related to natural products. A part of his thesis was done in the Structural Genomics Consortium, University of Oxford, in the group of Professor Stefan Knapp. From 2010 to 2017 he worked as a postdoctoral research fellow in the Pharmaceutical Chemistry laboratory of NKUA and the Pharmainformatics module of Athena Research Center having an on-going collaboration with the Target Discovery Institute of Oxford and the Goethe University of Frankfurt on the development of chemical probes for epigenetic targets.
He was appointed at his present position as Assistant Professor in 2019 and he was tenured in 2024. His current research is focused on the implementation of advanced theoretical simulations and biophysical methodologies toward the discovery and optimization of small molecules as potent and selective drug leads and chemical probes. His main research interests involve epigenetic protein modules and protein kinases.