Grissom JW, Gunawardena G, Gimisis T, Cismas C. N-(Trimethylsilyl)imidazole. In: Encyclopedia of Reagents for Organic Synthesis. American Cancer Society; 2007.


Abstract [18156-74-6] C6H12N2Si (MW 140.29) InChI = 1S/C6H12N2Si/c1-9(2,3)8-5-4-7-6-8/h4-6H,1-3H3 InChIKey = YKFRUJSEPGHZFJ-UHFFFAOYSA-N (silylating agent for alcohols and 1,3-dicarbonyl compounds; reaction with esters to give imidazolides; preparation of O-trimethylsilyl monothioacetals; aromatization of the A-ring of steroids) Physical Data: bp 93–94 °C/14 mmHg; fp 5 °C; d 0.956 g cm−3. Form Supplied in: liquid. Handling, Storage, and Precautions: flammable. Harmful by inhalation, in contact with skin, and if swallowed. Possible carcinogen. Use in a fume hood. When using, wear protective gear and clothing. Handle and store under N2. Store in a cool dry place.