Abstract:

{© 2019 Objective: To assess sleep disorders (SleD)in women with functional hypothalamic amenorrhoea (FHA)and to identify possible associations with known FHA predisposing factors. Study design: We conducted a prospective case-control study spanning the period January 2016 to April 2018. We recruited forty-one FHA women and 86 healthy controls. We assessed SleD and other FHA predisposing factors via self-reported questionnaires. The Spearman's correlation coefficient (rho)was used to examine possible correlations among the different variables. Multivariate logistic regression analysis was conducted to identify independent factors associated with SleD. Results: Women with FHA reported having higher SleD (p = 0.004), abnormal eating attitudes (p {\textless} 0.0001), higher anxiety levels (AL)(p {\textless} 0.0001), overweight preoccupation (P {\textless} 0.0001)and increased weekly physical activity (p = 0.004). There was a significant positive correlation between SleD and AL (rho = 0.88, p {\textless} 0.0001). Significant correlation was also found between AL and several Athens insomnia scale constituents, including sleep induction (rho = 0.53